COMPARISON OF MALONDIALDEHYDE LEVELS AMONG PATIENTS WITH SANDBLASTED ACID-ETCHED AND ANODIZED SURFACE DENTAL IMPLANTS: A PROSPECTIVE CLINICAL STUDY

Objective: Inflammation that occur as a part of body's response to implant-tissue contact can result in oxidative stress. Therefore, exploring the oxidative stress around different surface treated dental implants is essential to improve the performance of implants. The purpose of this study was to detect and measure the level of malondialdehyde (MDA), oxidative stress marker among SLA, SLActive and TiUnite implant surfaces. Materials and Methods: Subjects with healthy dental implant were categorized into Group 1: SLA (n=25), Group 2: SLActive (n=25), Group 3: TiUnite (n=25). Peri-implant crevicular fluid (PICF) was collected and MDA was quantified using ELISA kit. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s HSD post hoc. Results: The MDA level was high in group 3 (6.49±0.29 nmol/mL) followed by group 1 (5.37±0.47 nmol/mL) and group 2 (4.37±0.22 nmol/mL). There was a significant difference in MDA levels between the three groups (p = 0.00). Also, pairwise comparison showed a statistically significant difference between the groups (p = 0.00). Conclusion: Malondialdehyde level in peri-implant crevicular fluid was high around TiUnite dental implant as compared to SLA and SLActive implants.