纳米颗粒对幽门螺杆菌的抗菌活性:系统综述

Q2 Pharmacology, Toxicology and Pharmaceutics Current Bioactive Compounds Pub Date : 2023-10-31 DOI:10.2174/0115734072273911231010060747

Pegah Shakib, Reza Saki, Gholamreza Goudarzi, Mohammad Reza Zolfaghari

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引用次数: 0

摘要

背景:纳米颗粒对幽门螺杆菌的作用。方法:2名研究人员提取2000 - 2023年在Scopus、PubMed、Science Direct、Cochrane、Ovid等数据库中发表的关键词为幽门螺杆菌、H.pylori、纳米颗粒、固体脂质NPS、脂质纳米载体等的所有论文，并将其转移到EndNote X9软件中。结果:第一阶段共入选论文280篇。在应用纳入/排除的资格标准后，考虑到删除重复、不相关的文章和包含完整文本的研究，最终选择了37项研究。在目前的系统综述研究中，大多数用于治疗幽门螺杆菌的纳米颗粒是聚合物基纳米颗粒。结论:不同纳米颗粒对幽门螺杆菌具有较强的抑菌活性。因此，研究结果表明，这些纳米颗粒具有制备抗幽门螺杆菌纳米颗粒的潜力。此外，这些纳米颗粒的副作用比化学药物少。

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The Antimicrobial Activities of Nanoparticles against Helicobacter Pylori: A Systematic Review

Background: nanoparticles against Helicobacter pylori in the world. Therefore, this systematic review aims to investigate nanoparticles' antimicrobial activities against Helicobacter pylori Methods: All articles published from 2000 to 2023 from Scopus, PubMed, Science Direct, Cochrane, and Ovid databases with keywords Helicobacter pylori, H.pylori, nanoparticles, solid lipid NPS, and lipid nanocarrier were extracted and transferred to EndNote X9 software by two researchers. Results: During the first stage, 280 articles were chosen. Following the application of the eligibility criteria for inclusion/exclusion, 37 studies were ultimately selected, considering the removal of duplicates, irrelevant articles, and those containing complete text. In the present systematic review study, most nanoparticles used against Helicobacter pylori were polymericbased nanoparticles. Conclusion: The results indicate the high potential of various nanoparticles against Helicobacter Pylori. Therefore, the results show that these nanoparticles have the potential to prepare antiHelicobacter Pylori nanoparticles. In addition, these nanoparticles have fewer side effects than chemical drugs.

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来源期刊

Current Bioactive Compounds Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

1.90

自引率

0.00%

发文量

112

期刊介绍： The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.