乳腺癌的磁共振灌注成像

IF 1.5 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Magnetic Resonance Imaging Clinics of North America Pub Date : 2023-10-19 DOI:10.1016/j.mric.2023.09.012
Durga Udayakumar PhD, Ananth J. Madhuranthakam PhD, Başak E. Doğan MD
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引用次数: 0

摘要

乳腺癌是全世界妇女中最常见的癌症,给社会经济带来沉重负担。乳腺癌是一种异质性疾病,有4种主要亚型。每种亚型都有独特的预后因素、风险、治疗反应和生存率。靶向治疗的进步大大提高了原发性乳腺癌患者的5年生存率,这主要是由于广泛的筛查项目使早期发现和及时治疗成为可能。成像技术在诊断和治疗乳腺癌中是不可或缺的。虽然乳房x光检查是主要的筛查工具,但当乳房x光检查结果不确定或乳腺组织致密时,MRI发挥重要作用。MRI已成为乳腺癌成像的标准,提供详细的解剖和功能数据,包括肿瘤灌注和细胞结构。乳腺肿瘤的一个关键特征是血管生成,这是一个促进肿瘤发育和生长的生物学过程。肿瘤血管生成增加通常预示预后不良和转移风险增加。动态对比增强(DCE) MRI测量肿瘤灌注,并作为血管生成的体内指标。DCE-MRI已成为乳腺MRI的基石,尽管其特异性不同,但其阴性预测值高达89%至99%。本文综述了磁共振(MR)灌注成像在乳腺癌中的应用,重点介绍了DCE-MRI在临床应用中的作用,并探讨了新兴的MR灌注成像技术。
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来源期刊
Magnetic Resonance Imaging Clinics of North America
Magnetic Resonance Imaging Clinics of North America RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.10
自引率
0.00%
发文量
86
审稿时长
12 months
期刊介绍: Magnetic Resonance Imaging Clinics of North America updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced editor, each issue focuses on a single topic in magnetic resonance imaging including head and neck, breast, cardiac, chest, shoulder, hip, knee, abdomen, gastrointestinal, genitourinary, and soft tissue. In addition, you can also purchase a CME subscription that offers up to 60 AMA Category 1 credits per year.
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