纳米银生物传感器的现状与展望

Pub Date : 2023-10-11 DOI:10.1142/s1793984423300078
Rama Sharma
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引用次数: 0

摘要

由于其独特的光势、可控的等离子体特性、对尺寸和形状的控制,以及操纵其局部表面等离子体共振(LSPR)及其对周围环境的响应的能力,纳米银在生物传感器领域受到了特别的关注。银(Ag)是一个有吸引力的工具,在许多领域,包括诊断,药物输送,环境,电子,并作为一种抗菌剂。银纳米颗粒在生物传感器领域的应用是无处不在的。许多研究已经证明了使用银纳米颗粒提高临床指标特异性检测的有效性。纳米技术的发展极大地促进了生物传感器领域的发展,因为纳米材料具有较高的表面体积比,使其具有更高的灵敏度和效率。利用生物学、化学和材料科学的跨学科研究,纳米技术的最新进展鼓励了各种形状和尺寸的纳米材料的制造。在疾病诊断的背景下,这篇综述强调了银纳米颗粒在生物传感器中的应用,以检测小分子到更大的整个细胞。本文还讨论了如何提高葡萄糖生物传感器的灵敏度。它描述了如何提高包括DNA、蛋白质、微小分子和完整细胞在内的生物分子的检测性能。对于未来在诊断领域的应用,这篇综述有助于全面了解银纳米颗粒的临床重要性。这些生物传感器可用于诊断领域,以加快响应时间。
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Current understanding and prospects of silver nanoparticles-based Biosensor
Due to their distinctive optical potential, controlled plasmonic features, control over size and shape, and ability to manipulate their localized surface plasmon resonance (LSPR) and their response to their surroundings, silver nanoparticle attracts special attention in the fields of the biosensor. Silver (Ag) is an appealing tool in many domains, including diagnosis, medicine delivery, environment, electronics, and as an antibacterial agent. Ag nanoparticle applications are ubiquitous today in the fields of biosensors. Numerous studies have demonstrated the effectiveness of using Ag nanoparticles to improve the specific detection of clinical indicators. The development of nanotechnology has greatly benefited the field of biosensors since nanomaterials have a high surface-to-volume ratio that enables them to operate with greater sensitivity and effectiveness. Utilizing interdisciplinary study in biology, chemistry, and material science, recent advancements in nanotechnology encouraged the manufacture of nanomaterials in a variety of shapes and sizes. In the context of disease diagnosis, this review highlighted the use of Ag nanoparticles in biosensors to detect small molecules to bigger entire cells. This paper also discusses how to make a glucose biosensor more sensitive. It describes how the detection performance of biomolecules including DNA, protein, tiny molecules, and complete cells can be improved. For future applications in the field of diagnosis, this review helps in developing an overall understanding of the clinical importance of Ag nanoparticles. These biosensors can be implemented in the field of diagnosis to speed up the response time.
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