长期通气创伤后急性呼吸窘迫综合征患者超声脱机标准与常规脱机标准的比较研究

Mohamed Gaber Ibrahim Mostafa Allam
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引用次数: 0

摘要

在重症监护病房(ICU)中,断奶和再通气失败是一个主要问题。30%的通气患者经历脱机失败并重新通气,特别是长时间通气的患者。超声提供肺实质炎症消退和膈肌收缩力的可靠数据,从而有助于决定患者是否应该断奶,从而降低断奶失败的百分比。工作目的:比较长时间通气的创伤后急性呼吸窘迫综合征(ARDS)患者超声脱机标准与常规脱机标准,并评价其对ICU住院时间的影响。材料和方法:这是一项前瞻性、双盲研究,对200名受试者进行了研究,这些受试者在通气1小时后脱离呼吸机;1周因呼吸衰竭。患者的呼吸衰竭是由严重的肺挫伤或创伤后ARDS引起的。患者被随机平均地分为两组,每组100名患者。A组和B组分别采用常规和超声脱机标准脱离呼吸机。两组患者均脱机后随访6天,观察脱机失败和拔管后呼吸衰竭的迹象。记录两组患者再通气及出院人数并进行比较。结果:A组患者出现意识恶化、呼吸急促、去饱和、心动过速、高血压、胸部x线浸润及再通气的人数明显高于B组,且A组患者在ICU的持续时间明显高于B组。结论:超声脱机标准可减少再插管、再通气和拔管后呼吸衰竭。此外,它的使用还减少了创伤后ARDS患者长期通气的ICU住院时间。
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Comparative Study between the use of Ultrasonic Criteria of Weaning versus the Conventional Criteria of Weaning in Post-traumatic Acute Respiratory Distress Syndrome Patients who were Ventilated for a long Time
Introduction: Failure to wean and re-ventilation is a major problem in the intensive care unit (ICU). Thirty percent of ventilated patients experience weaning failure and are re-ventilated, especially patients who are ventilated for long durations. Ultrasound provides reliable data on lung parenchyma inflammation resolution and diaphragmatic contraction power, thereby assisting in deciding if the patient should be weaned and consequently reducing the percentage of weaning failure. Aim of the Work: To compare the ultrasonic criteria for weaning with the conventional criteria of weaning in patients with post-traumatic acute respiratory distress syndrome (ARDS) who were ventilated for a long time and assess their effect on the ICU stay duration. Materials and Methods: This was a prospective, double-blind study performed on 200 participants who were weaned from the ventilator after being ventilated for > 1 week due to respiratory failure. Respiratory failure in the patients was either due to severe lung contusion or post-traumatic ARDS. The patients were randomly and equally allocated in two groups of 100 patients each. Groups A and B comprised patients who were weaned from the ventilator using the conventional and ultrasound weaning criteria, respectively. All patients weaned from both groups were followed up for 6 days for signs of weaning failure and post-extubation respiratory failure. The number of patients who were re-ventilated and discharged from the ICU was recorded and compared in both groups. Results: Group A had a significantly higher number of patients who experienced deterioration in consciousness, tachypnea, desaturation, tachycardia, and hypertension in addition to showing chest X-ray infiltration and being re-ventilated than group B. Moreover, group A patients had a significantly longer ICU duration than group B patients. Conclusion: The use of the ultrasonic criteria for weaning reduces re-intubation, re-ventilation, and post-extubation respiratory failure. Additionally, its use also decreases the ICU stay in patients with post-traumatic ARDS who were ventilated for a long time.
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