{"title":"基于无标签光学原理的谐振波导光栅生物传感器","authors":"Igor Sallai","doi":"10.3311/ppee.22878","DOIUrl":null,"url":null,"abstract":"Label-free optical biosensors are powerful tools for the real-time monitoring of both molecular and cellular-scale interactions. Resonant waveguide grating biosensors are based on the detection of refractive index changes induced by molecular interactions and/or cell mass redistributions. The Epic BenchTop and Epic Cardio are two biosensors with high sensitivity and throughput that offer excellent potential for life science research. Both instruments are suitable for cell-based and biochemical assays. In this paper, I describe the principles of operation and performance of the Epic BenchTop and Epic Cardio label-free waveguide grating biosensors and discuss their applications in various research areas.","PeriodicalId":37664,"journal":{"name":"Periodica polytechnica Electrical engineering and computer science","volume":"58 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Resonant Waveguide Grating Biosensors Based on Label-free Optical Principle\",\"authors\":\"Igor Sallai\",\"doi\":\"10.3311/ppee.22878\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Label-free optical biosensors are powerful tools for the real-time monitoring of both molecular and cellular-scale interactions. Resonant waveguide grating biosensors are based on the detection of refractive index changes induced by molecular interactions and/or cell mass redistributions. The Epic BenchTop and Epic Cardio are two biosensors with high sensitivity and throughput that offer excellent potential for life science research. Both instruments are suitable for cell-based and biochemical assays. In this paper, I describe the principles of operation and performance of the Epic BenchTop and Epic Cardio label-free waveguide grating biosensors and discuss their applications in various research areas.\",\"PeriodicalId\":37664,\"journal\":{\"name\":\"Periodica polytechnica Electrical engineering and computer science\",\"volume\":\"58 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Periodica polytechnica Electrical engineering and computer science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3311/ppee.22878\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Computer Science\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Periodica polytechnica Electrical engineering and computer science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3311/ppee.22878","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Computer Science","Score":null,"Total":0}
Resonant Waveguide Grating Biosensors Based on Label-free Optical Principle
Label-free optical biosensors are powerful tools for the real-time monitoring of both molecular and cellular-scale interactions. Resonant waveguide grating biosensors are based on the detection of refractive index changes induced by molecular interactions and/or cell mass redistributions. The Epic BenchTop and Epic Cardio are two biosensors with high sensitivity and throughput that offer excellent potential for life science research. Both instruments are suitable for cell-based and biochemical assays. In this paper, I describe the principles of operation and performance of the Epic BenchTop and Epic Cardio label-free waveguide grating biosensors and discuss their applications in various research areas.
期刊介绍：
The main scope of the journal is to publish original research articles in the wide field of electrical engineering and informatics fitting into one of the following five Sections of the Journal: (i) Communication systems, networks and technology, (ii) Computer science and information theory, (iii) Control, signal processing and signal analysis, medical applications, (iv) Components, Microelectronics and Material Sciences, (v) Power engineering and mechatronics, (vi) Mobile Software, Internet of Things and Wearable Devices, (vii) Solid-state lighting and (viii) Vehicular Technology (land, airborne, and maritime mobile services; automotive, radar systems; antennas and radio wave propagation).
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