核酸和蛋白质功能域的距离分析和序列特性

Andrzej K. Konopka, Devjani Chatterjee
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引用次数: 10

摘要

我们提出了一种统一的算法来分析核酸和蛋白质序列中短低聚物之间的距离(DISTANP)。这个扩展版本的DISTAN方法不仅允许分析选定的低聚物对之间的距离,而且还允许用户分析残基组之间的距离(如酸性和疏水氨基酸)。这种能力允许区分核酸和蛋白质中已知功能域的序列特性。
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Distance analysis and sequence properties of functional domains in nucleic acids and proteins

We present a unified algorithm to analyze distances between short oligomers in large collections of nucleic acids and protein sequences (DISTANP). This extended version of DISTAN methodology not only permits analysis of distances between selected pairs of oligomers, but also allows a user to analyze distances between groups of residues (such as acidic and hydrophobic amino acids). This capacity allows differentiation of sequence properties of known functional domains in nucleic acids and proteins.

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