{"title":"皮肤基底细胞瘤的诊断方法:鳞状细胞是红色的,基底细胞是蓝色的,但唉!如果这是真的就好了","authors":"Yi Ariel Liu, Ana Mercedes Ciurea, Phyu P Aung","doi":"10.1016/j.mpdhp.2023.10.006","DOIUrl":null,"url":null,"abstract":"<div><p>Basaloid neoplasms of the skin are often challenging not only to general pathologists but also dermatopathologists especially in the setting of partial sampling. While basal cell carcinomas make up most cutaneous neoplasms, there is a wide variety of both benign and malignant entities that have a basaloid morphology, which are particularly important to distinguish when present on skin in sensitive areas. Distinguishing between the malignant from the benign requires an understanding of the clinical presentation, histological correlation, emergence of new subclassification, as well as molecular discoveries. This chapter will examine the common cutaneous basaloid neoplasms encountered in routine practice and will highlight pitfalls to avoid misdiagnosis of rare but aggressive mimics.</p></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"30 1","pages":"Pages 60-76"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1756231723001664/pdfft?md5=49966d059f1eeb59e7cb763d39a20055&pid=1-s2.0-S1756231723001664-main.pdf","citationCount":"0","resultStr":"{\"title\":\"A diagnostic approach to basaloid neoplasms of the skin: squamous is red; basals are blue but alas! If only that were true\",\"authors\":\"Yi Ariel Liu, Ana Mercedes Ciurea, Phyu P Aung\",\"doi\":\"10.1016/j.mpdhp.2023.10.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Basaloid neoplasms of the skin are often challenging not only to general pathologists but also dermatopathologists especially in the setting of partial sampling. While basal cell carcinomas make up most cutaneous neoplasms, there is a wide variety of both benign and malignant entities that have a basaloid morphology, which are particularly important to distinguish when present on skin in sensitive areas. Distinguishing between the malignant from the benign requires an understanding of the clinical presentation, histological correlation, emergence of new subclassification, as well as molecular discoveries. This chapter will examine the common cutaneous basaloid neoplasms encountered in routine practice and will highlight pitfalls to avoid misdiagnosis of rare but aggressive mimics.</p></div>\",\"PeriodicalId\":39961,\"journal\":{\"name\":\"Diagnostic Histopathology\",\"volume\":\"30 1\",\"pages\":\"Pages 60-76\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1756231723001664/pdfft?md5=49966d059f1eeb59e7cb763d39a20055&pid=1-s2.0-S1756231723001664-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic Histopathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1756231723001664\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231723001664","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A diagnostic approach to basaloid neoplasms of the skin: squamous is red; basals are blue but alas! If only that were true
Basaloid neoplasms of the skin are often challenging not only to general pathologists but also dermatopathologists especially in the setting of partial sampling. While basal cell carcinomas make up most cutaneous neoplasms, there is a wide variety of both benign and malignant entities that have a basaloid morphology, which are particularly important to distinguish when present on skin in sensitive areas. Distinguishing between the malignant from the benign requires an understanding of the clinical presentation, histological correlation, emergence of new subclassification, as well as molecular discoveries. This chapter will examine the common cutaneous basaloid neoplasms encountered in routine practice and will highlight pitfalls to avoid misdiagnosis of rare but aggressive mimics.
期刊介绍:
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.