{"title":"肝细胞癌DNA修复基因特征和潜在分子亚型的鉴定","authors":"Yutao Wang","doi":"10.52768/2379-1039/1991","DOIUrl":null,"url":null,"abstract":"DNA repair is a critical factor in tumor progression since it influences tumor mutational burden, genome stability, PD-L1 expression, tumor-infiltrating lymphocytes (TILs) and immunotherapy response. In this study, we constructed a prognostic model for hepatocellular carcinoma (HCC) based on DNA damage response (DDR)-related genes.","PeriodicalId":294824,"journal":{"name":"Open Journal of Clinical and Medical Case Reports","volume":"235 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Identification of DNA repair gene signature and potential molecular subtypes in hepatocellular carcinoma\",\"authors\":\"Yutao Wang\",\"doi\":\"10.52768/2379-1039/1991\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"DNA repair is a critical factor in tumor progression since it influences tumor mutational burden, genome stability, PD-L1 expression, tumor-infiltrating lymphocytes (TILs) and immunotherapy response. In this study, we constructed a prognostic model for hepatocellular carcinoma (HCC) based on DNA damage response (DDR)-related genes.\",\"PeriodicalId\":294824,\"journal\":{\"name\":\"Open Journal of Clinical and Medical Case Reports\",\"volume\":\"235 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Journal of Clinical and Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52768/2379-1039/1991\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Journal of Clinical and Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52768/2379-1039/1991","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Identification of DNA repair gene signature and potential molecular subtypes in hepatocellular carcinoma
DNA repair is a critical factor in tumor progression since it influences tumor mutational burden, genome stability, PD-L1 expression, tumor-infiltrating lymphocytes (TILs) and immunotherapy response. In this study, we constructed a prognostic model for hepatocellular carcinoma (HCC) based on DNA damage response (DDR)-related genes.
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