肥胖儿童与健康对照组前段参数的比较

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Konuralp Tip Dergisi Pub Date : 2023-06-22 DOI:10.18521/ktd.1194775
Mehmet Tahir ESKİ, Kuddusi TEBERİK, Taha SEZER, İlknur ARSLANOĞLU
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 Material and methods: 55 obese and 30 control group children subjects participated. All participants and the control group were examined and anthropometric measurements were made. The measurements of fasting blood glucose(FBG), triglyceride(TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and insulin values were performed. The homeostasis model assessment of insulin resistance (HOMA‑IR) was calculated. Each participant underwent a detailed ophthalmic examination and IOP, CCT, ACD and LT were measured.
 Results: The gender distribution of the groups was similar (p=0.893). The mean of CCT and LT were significantly higher in the obese group (572.9 ± 14.5 vs. 559.5 ± 10.1 µm, p=0.001; 3.6 ± 0.14 vs. 3.48 ± 0.25 mm, p=0.007) . No significant difference was found between the obese and control groups in terms of other parameters. BMI and WC had a significant negative correlation with LT control groups. The obese group showed a significant positive correlation between IOP and TG (r=0.276, p=0.042), and a significant negative correlation with HDL-C (r=-0.273, p=0.043). In the control group, there was a significant positive correlation between IOP and BMI (r=0.389, p=0.034), WC (r=0.497, p=0.005), HOMA-IR (r=0.384, p=0.036), Insulin (r=0.407, p=0.026), and a significant negative correlation with TC (r=-0.511, p=0.004). A significantly positive correlation between ACD and LDL-C (r=0.371, p=0.043) and a significantly negative correlation between HOMA-IR in the control group were detected (r=-0.682, p=0.000).
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引用次数: 0

摘要

目的:评价肥胖儿童前段参数;材料与方法:肥胖儿童55例,对照组儿童30例。所有的参与者和对照组都进行了检查,并进行了人体测量。测定空腹血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)和胰岛素值。计算胰岛素抵抗的稳态模型评估(HOMA‑IR)。每位参与者均接受详细的眼科检查,并测量IOP、CCT、ACD和LT。 结果:两组患者性别分布相似(p=0.893)。肥胖组CCT和LT的平均值显著高于肥胖组(572.9±14.5 vs 559.5±10.1µm, p=0.001;3.6±0.14 vs. 3.48±0.25 mm, p=0.007)。在其他参数方面,肥胖组和对照组之间没有发现显著差异。BMI、WC与LT对照组呈显著负相关。肥胖组IOP与TG显著正相关(r=0.276, p=0.042),与HDL-C显著负相关(r=-0.273, p=0.043)。对照组IOP与BMI (r=0.389, p=0.034)、WC (r=0.497, p=0.005)、HOMA-IR (r=0.384, p=0.036)、胰岛素(r=0.407, p=0.026)呈正相关,与TC (r=-0.511, p=0.004)呈显著负相关。对照组患者ACD与LDL-C呈显著正相关(r=0.371, p=0.043), HOMA-IR呈显著负相关(r=-0.682, p=0.000)。结论:肥胖组CCT和LT均高于对照组。
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Comparison of Anterior Segment Parameters in Obese Children And Healthy Control Group
Objective:: To evaluate anterior segment parameters in obese children Material and methods: 55 obese and 30 control group children subjects participated. All participants and the control group were examined and anthropometric measurements were made. The measurements of fasting blood glucose(FBG), triglyceride(TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and insulin values were performed. The homeostasis model assessment of insulin resistance (HOMA‑IR) was calculated. Each participant underwent a detailed ophthalmic examination and IOP, CCT, ACD and LT were measured. Results: The gender distribution of the groups was similar (p=0.893). The mean of CCT and LT were significantly higher in the obese group (572.9 ± 14.5 vs. 559.5 ± 10.1 µm, p=0.001; 3.6 ± 0.14 vs. 3.48 ± 0.25 mm, p=0.007) . No significant difference was found between the obese and control groups in terms of other parameters. BMI and WC had a significant negative correlation with LT control groups. The obese group showed a significant positive correlation between IOP and TG (r=0.276, p=0.042), and a significant negative correlation with HDL-C (r=-0.273, p=0.043). In the control group, there was a significant positive correlation between IOP and BMI (r=0.389, p=0.034), WC (r=0.497, p=0.005), HOMA-IR (r=0.384, p=0.036), Insulin (r=0.407, p=0.026), and a significant negative correlation with TC (r=-0.511, p=0.004). A significantly positive correlation between ACD and LDL-C (r=0.371, p=0.043) and a significantly negative correlation between HOMA-IR in the control group were detected (r=-0.682, p=0.000). Conclusion: The obese group had higher CCT and LT than the control groups.
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Konuralp Tip Dergisi
Konuralp Tip Dergisi MEDICINE, GENERAL & INTERNAL-
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