病例报告及文献回顾:一例罕见的姑息病人结肠支架失效

Morgan Bressington, Alexander O’Connor, Karen Telford
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摘要

对于姑息治疗患者,一个整体的方法是重要的。干预措施应尽量缩短住院时间,提高生活质量,并控制症状。用于恶性大肠梗阻(MLBO)姑息治疗的自膨胀金属支架(SEMS)旨在为接近生命终点的患者提供这些益处。我们报告一位患者在2年前因MLBO接受SEMS治疗的病例。他在诊断时接受了姑息治疗,因为他的虚弱和医疗合并症使手术无法进行。他后来出现了严重的下坠,这些新症状后来被发现是由于一个罕见的支架失效,支架已经断裂,无法恢复。在7个月后患者不幸去世之前,必须对其进行保守治疗。SEMS被认为是缓解不能手术的左侧结肠癌引起的MLBO的一线治疗方法。与去功能造口相比,这种治疗缩短了住院时间,减少了造口率,减少了并发症,生存率也相当。但是,预计自动售货机不会长期使用。文献报道,在姑息环境下,结肠支架置入后的平均生存期为121至199天。结论:这是首次报道结肠支架置入2年后失效的病例之一。这个案例表明,进一步研究这种治疗方案的长期结果是有必要的,特别是姑息治疗患者的寿命更长。
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Case report and narrative review of the literature: a rare colonic stent failure in a palliative patient
Introduction With palliative patients, a holistic approach is important. Interventions should minimise length of hospital stay, maximise quality of life, and control symptoms. A self-expanding metal stent (SEMS) for the palliative treatment of malignant large bowel obstruction (MLBO) is designed to provide these benefits to patients approaching the end of their life. We present the case of a patient treated with a SEMS over 2 years earlier for MLBO. He was treated with palliative intent at diagnosis because his frailty and medical co-morbidities precluded surgery. He later presented with severe tenesmus, and these new symptoms were later found to be due to a rare stent failure in which the stent had fractured and was irretrievable. This had to be managed conservatively before the patient sadly passed away 7 months later. Discussion A SEMS is considered the first-line treatment to relieve MLBO caused by inoperable left-sided colonic cancer. This treatment offers a reduced length of hospital stay, reduced stoma rates, fewer complications, and comparable survival compared to de-functioning stoma. However, SEMSs are not expected to be in use for extended periods of time. The literature reports an average survival after a colonic stent insertion of between 121 and 199 days when used in a palliative setting. Conclusion This is one of the first case reports to describe a colonic stent failure occurring over 2 years after insertion. This case argues that further research into the longer-term outcomes of this management option is warranted, particularly as palliative patients are living longer.
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