巴厘岛曼达拉医院重症猪链球菌脑膜炎1例报告

I Wayan Agus Gede Manik Saputra, Indira Chadijah Triatmoko, I Gede Eka Widarmawan, I Gede Hermawan, Putu Dwi Adi
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摘要

背景:猪链球菌脑膜炎(SSM)是一种严重的人畜共患疾病。许多SSM病例的主要危险因素与养猪和食用未煮熟的猪肉产品有关。在印度尼西亚,特别是在巴厘岛,这种急性细菌性脑膜炎病例与食用称为“红拉瓦”的巴厘岛传统食物密切相关,这种食物是由生猪肉、新鲜猪肉血和传统巴厘岛草药混合而成。本研究旨在报告一例在巴厘岛曼达拉医院的SSM。病例描述:一名63岁男性因意识下降(格拉斯哥昏迷评分3/15)而入院急诊室。该患者因感染性休克疑似急性细菌性脑膜炎从私立医院转院。入院前2天出现发热、头痛、咳嗽等相关症状。在出现症状前2天,他也有食用"红laww "的历史。脑脊液分析和化脓性标志物的实验室结果表明患者患有细菌性脑膜炎。患者最初因感染性休克而开始使用美罗培南。一旦培养和敏感性试验完成并产生猪链球菌,广谱抗生素就降级为头孢曲松。头孢曲松作为最终治疗疗程14天,临床改善,无SSM感染相关的特异性后遗症,如听力损失。结论:重症脑膜炎如猪链球菌导致的感染性休克是一种危及生命的健康状况。适当的抗生素治疗和多学科联合治疗可降低此病的死亡率和发病率。
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Severe case of Streptococcus suis meningitis in Bali Mandara Hospital: a case report
Background: Streptococcus suis meningitis (SSM) is one of the zoonotic disease that can cause serious illness in humans. The major risk factor in many cases of SSM is associated with pig husbandry and consuming undercooked pork products. In Indonesia, especially in Bali, the cases of this acute bacterial meningitis has been strongly correlated with consuming Balinese traditional food called “red lawar”, a mixture of raw pork, fresh pork blood and traditional Balinese herbs. This study aims to report a case of SSM in Bali Mandara Hospital. Case description: A 63-year-old man admitted to the Emergency Department because of a decrease in consciousness (Glasgow coma scale 3/15). This patient was transferred from a private hospital with septic shock and suspicious to acute bacterial meningitis. He had other related symptoms like fever, headache, and cough since two days prior to admission. He also had a history of consuming “red lawar” 2 days before the symptoms appeared. Laboratory findings from cerebrospinal fluid analysis and septic marker indicate the patient had bacterial meningitis. The patient was initially started by Meropenem due to his septic shock. The broad spectrum antibiotics were then de-escalate to Ceftriaxone once the culture and sensitivity test completed and yielded Streptococcus suis. The course of Ceftriaxone as definitive therapy has been administered for 14 days and showed clinical improvement without specific sequelae related to SSM infection like hearing loss. Conclusion: Severe meningitis e.c Streptococcus suis leading to septic shock is a life threatening health condition. Adequate antibiotic therapy and multidisciplinary approach can reduce mortality and morbidity of this case.
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