[治疗引起的母乳林丹浓度]。

E Senger, I Menzel, H Holzmann
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引用次数: 0

摘要

不同的作者报道了林丹(γ -六氯环己烷)治疗婴儿后引起的神经毒性反应。这导致了关于婴儿早期林丹治疗适应症的争议性讨论。据我们所知,迄今为止还没有发表过关于局部疥疮治疗后母乳中林丹浓度的报告。在一位用林丹治疗疥疮的母亲身上,我们发现母乳中的林丹含量升高。与母乳中林丹的平均水平(0.03 ppm,乳脂)相比,在3天的治疗后,林丹的含量增加了30倍,在另外一天的治疗后,林丹的含量增加了66倍。讨论了出现的问题和替代疗法。
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[Therapy-induced lindane concentration in breast milk].

Reactions induced by neurotoxic effects with lindane (gamma-hexachlorcyclohexane) after treatment of infants have been reported by different authors. This has led to controversial discussions as to the indication for therapy with lindane in early infancy. To our knowledge there are to date no published reports on the concentration of lindane in mother's milk after local scabies therapy. In a mother treated with lindane for scabies we found elevated levels of lindane in the mother's milk. Compared to average levels of lindane in mother's milk (0.03 ppm, milk-fat) there was a 30-fold increase after three-day treatment and a 66-fold elevation after an additional one-day treatment with lindane. The problems arising and alternative therapy are discussed.

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