瑜伽运动降低多囊卵巢综合征(PCOS)胰岛素抵抗患者Homa-Ir和胰岛素水平

None Zakkiyatus Zainiyah, None Muhammad Suhron
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摘要

背景:多囊卵巢综合征(PCOS)是一种以高雄激素血症、慢性无排卵、多囊卵巢形态(PCOM)为特征的生殖女性不孕症内分泌疾病,多数PCOS患者伴有代谢紊乱。HOMA-IR是评价胰岛素抵抗型PCOS患者卵巢功能的一项简便、灵敏的临床指标。HOMA-IR检查从未在马杜罗和印度尼西亚对肥胖的多囊卵巢综合征患者进行过,之所以在马杜罗进行,是因为多囊卵巢综合征患者有肥胖的可能性,并且有高碳水化合物摄入等不良生活方式和肥胖倾向。目的:本研究的目的是分析瑜伽运动对降低胰岛素抵抗型多囊卵巢综合征(PCOS)患者HOMA-IR和胰岛素水平的影响。方法:采用病例对照研究设计,选取Madurese部落50例多囊卵巢综合征(PCOS)患者和50例健康女性(非PCOS),测定血清HOMA-IR和胰岛素水平,并在实验室进行检测。卡方检验,显著性0.05。结果:卡方统计检验显示,病例组在进行瑜伽运动前HOMA-IR平均为40.97,胰岛素水平为61.38?而对照组的平均HOMA-IR结果为1.54,平均胰岛素水平为2.9-21?1 /ml,每周2次,每次12次。结论:HOMA-IR值和胰岛素水平均有降低。病例组在进行体操运动前后HOMA-IR值和胰岛素水平下降。
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Yoga Exercises in Reduce Homa-Ir and Insulin Levels in Polycystic Ovarium Syndrome (PCOS) Insulin Resistant
Background: Polycystic Ovary Syndrome (PCOS), an endocrine disease that causes infertility in reproductive women, characterized by hyperandrogenemia, chronic anovulation, and Polycystic Ovary Morphology (PCOM), most PCOS women have metabolic disorders. The HOMA-IR can be used as a clinical index that is easy and sensitive to assess ovarian function in insulin-resistant PCOS women. The HOMA-IR examination has never been performed on obese PCOS patients in Madurese and Indonesia, it was carried out in Madura because it has the potential for obesity with unfavorable lifestyles such as consuming high carbohydrates and a tendency to obesity in PCOS patients. Purpose: The aim of this study was to analyze yoga exercises in reducing HOMA-IR and Insulin Levels in insulin-resistant polycystic ovary syndrome (PCOS) in the Madurese. Methods: Analytic observational study with a case-control study design, a sample of 50 patients (cases of PCOS) and 50 healthy women (non-PCOS) in the Madurese tribe, serum was taken to check HOMA-IR and insulin levels, which were examined in the laboratory. Chi-square statistical test with significance 0.05. Results: The results Chi-square statistical test with significance 0.05 showed that the case group before being given Yoga exercises the average HOMA-IR results were 40.97 and insulin levels were 61.38?l/ml while in the control group the average HOMA-IR results were 1.54 and average insulin levels were 2.9-21?l /ml, after doing Yoga exercises for 12 times and 2 times a week. Conclusion: There is a decrease in the HOMA-IR value and insulin levels. The HOMA-IR values and insulin levels decreased between before and after being given gymnastics in the case group.
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