特发性震颤和衰老

Nicki Niemann, Holly A. Shill
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摘要

特发性震颤(ET)是一种非常常见的神经系统疾病,随着年龄的增长而增加。随着年龄的增长,震颤的严重程度和身体分布都有变化。ET患者可能出现小脑功能障碍的临床症状。其他神经学症状也可以看到,但它们与ET的联系还没有完全确定。小脑的病理改变可见ET,尽管将ET描述为神经退行性疾病还为时过早。与其他神经退行性疾病,如阿尔茨海默氏症和帕金森氏症的联系可以看到,但可能只是反映了衰老的巧合共病。
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Essential tremor and ageing
Essential Tremor (ET) is a very common neurological condition that increases with age. Tremor progresses in severity and body distribution with aging. Patients with ET may develop clinical signs of cerebellar dysfunction. Other neurological signs may be seen as well, but their association with ET has not been fully solidified. Pathological changes in the cerebellum are seen with ET, although describing ET as a neurodegenerative disease is still premature. Links to other neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease can be seen but may simply reflect co-incidental co-morbidities of aging.
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