化疗和放疗作用下反应扩散模型的集值稳定

Amine MOUSTAFİD
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引用次数: 0

摘要

本文旨在控制偏微分方程,模拟肿瘤化疗和/或放疗,从而使肿瘤密度渐近稳定。利用初始条件集上一般模型的生存核来求解控制问题,并将控制解表征为调节映射的调节律。本文考虑了文献中的三个模型来模拟结果。第一个模型包括化疗对logistic肿瘤增殖的影响,第二个模型显示了放疗对肿瘤指数增长的影响,第三个模型显示了化疗和放疗联合对Gompertzian肿瘤生长的影响。
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Set-Valued Stabilization of Reaction-Diffusion Model by Chemotherapy and or Radiotherapy
This paper aims to control partial differential equations, modeling cancer chemotherapy and or radiotherapy, so in order to asymptotically stabilize the tumor density. Viability kernel of general model on set of initial condition is used to solve the control problem, and characterize the control solution as regulation law of regulation map. Three models from the literature are considered to simulate the results. The first model includes chemotherapy effect on logistic tumor proliferation, while the second one demonstrates radiotherapy effect on exponential tumor increasing, whereas the third one models the effects of the combination of chemotherapy and radiotherapy on Gompertzian tumor growth.
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