苹果醋作为功能性食品对糖尿病患者人体测量指标及血糖、血脂的改善作用:一项随机对照临床试验

Sima Jafarirad, Mohammad-Reza Elahi, Anahita Mansoori, Abdollah Khanzadeh, Mohammad-Hossein Haghighizadeh
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引用次数: 0

摘要

背景:每年在治疗和预防糖尿病的进展上花费了大量的医疗费用。苹果醋(ACV)对餐后高血糖有积极作用。本研究旨在评估长期服用ACV对2型糖尿病患者血糖指标和血脂的影响。方法本研究为随机临床试验,受试者为2型糖尿病成人患者。参与者被分为两组:ACV组和对照组。ACV组给予ACV 30 ml / d治疗。干预组和对照组都得到了同样的健康饮食建议。8周前后分别测定空腹血糖、胰岛素、血红蛋白A1C、胰岛素抵抗、总胆固醇(Chol)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯。结果两组干预后空腹血糖均有降低,仅ACV组有显著性差异(p = 0.01)。两组患者血红蛋白A1C水平差异有统计学意义(p <0.001)。ACV组LDL降低(p <0.001)。干预期后,ACV组的Total Chol、LDL/HDL、Chol/HDL比值均低于对照组(p = 0.003、p = 0.001、p = 0.001)。结论每日服用ACV对控制2型糖尿病患者血糖指标及血脂有有益作用。临床试验注册http://www.irct.ir,标识符IRCT20140107016123N13。
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The improvement effect of apple cider vinegar as a functional food on anthropometric indices, blood glucose and lipid profile in diabetic patients: a randomized controlled clinical trial
Background Numerous medical costs are spent each year on treating and preventing the progression of diabetes. The positive effect of apple cider vinegar (ACV) has been shown on post-prandial hyperglycemia. This study aimed to evaluate the effects of prolonged consumption of ACV on blood glucose indices and lipid profile in patients with type 2 diabetes. Methods This study was a randomized clinical trial and the participants were adults with type 2 diabetes. Participants were divided into two groups: ACV and control. The ACV group was treated with 30 ml of ACV per day. Both the intervention and control groups received the same recommendation for a healthy diet. Before and after eight weeks, fasting blood glucose, insulin, hemoglobin A1C, insulin resistance, total cholesterol (Chol), low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride were measured. Results Fasting blood glucose decreased after intervention in both groups, which was only significant in the ACV group (p = 0.01). There was a significant difference in hemoglobin A1C levels between the two groups (p &lt; 0.001) after eight weeks. LDL was decreased in the ACV group (p &lt; 0.001). Total Chol, LDL/HDL and Chol/HDL ratio decreased after the intervention period in the ACV group compared to the control group (p = 0.003, p = 0.001 and p = 0.001, respectively). Conclusion Daily consumption of ACV may have beneficial effects in controlling blood glucose indices and lipid profile in patients with type 2 diabetes. Clinical trial registration http://www.irct.ir , identifier IRCT20140107016123N13.
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