与成人患者2型糖尿病合并症相关的因素:尼日利亚阿布贾一家医疗中心的回顾性临床审计

Eze D Ukah, Emmanuel S Oguntade, Damilare M Oladimeji
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Using the electronic medical records, key variables of interest were extracted, and the effects of comorbid conditions on Type 2 Diabetes Mellitus (T2DM) were determined. Results The summary results revealed that the incidence of T2DM was approximately 107(66.1%) had T2DM, while about 159 (98.2%) out of the 162 patients with one or more other diseases had T2DM. There were more female patients, 97(59.9%) with cases of DM than male patients. Patients aged 40-69 years have more prevalence cases of DM (73.5%), with those engaging in businesses or trading common in this category (29.63%). Most of these patients had Hypertension as a comorbid condition 110(67.9). The results based on the logistic model showed that patients with concordant comorbid conditions are 2.11 times more likely to develop T2DM. 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引用次数: 0

摘要

背景:糖尿病(DM)是一种代谢紊乱,其中胰岛素的绝对或相对缺乏导致高血糖,导致急性和慢性并发症。多年来,全球不同地区的糖尿病发病率问题已成为一个巨大的公共卫生问题,特别是在患有合并症的患者中。这些情况使得DM的治疗和管理极为困难,特别是在卫生系统薄弱的撒哈拉以南非洲地区。方法本研究是一项回顾性研究,基于在贾比阿布贾联邦医疗中心接受治疗的162例患者的记录回顾。利用电子病历,提取关键变量,并确定合并症对2型糖尿病(T2DM)的影响。结果T2DM的发生率约为107例(66.1%),162例合并其他一种或多种疾病的患者中约有159例(98.2%)为T2DM。女性患者多于男性患者,97例(59.9%)。40-69岁的糖尿病患者患病率较高(73.5%),从事商业或贸易的患者在这一类别中常见(29.63%)。这些患者中大多数合并高血压110(67.9)。基于logistic模型的结果显示,具有一致性合并症的患者发展为T2DM的可能性高出2.11倍。贝叶斯logistic回归模型显示性别与合并症呈正相关;男性患者出现合并症的可能性是男性的1.65倍,有吸烟史的患者出现合并症的可能性是男性的1.56倍。T2DM与收缩压无关。结论:本研究提供了研究地区及其周边地区糖尿病发病率和相关合并症的详细信息。基于目前的发现,贝叶斯模型似乎比传统的逻辑回归更准确。反过来,这可以用来制定卫生政策,以有效管理、控制和预防尼日利亚任何类型的糖尿病,并提高社区对糖尿病的认识。
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Factors associated with type 2 diabetes mellitus comorbidity among adult patients: a retrospective clinical audit of a medical centre in Abuja, Nigeria
Background Diabetes mellitus (DM) is a disorder of metabolism in which an absolute or relative deficiency of insulin results in hyperglycemia leading to acute and chronic complications. Over the years, the issue of incidences of DM in different regions of the globe has become a huge public health problem, especially in cases of patients with comorbidity conditions. These conditions have made the treatment and management of DM extremely difficult, especially in sub-Saharan Africa, where there are weak health systems. Methods This study was a retrospective study based on the record review of 162 patients receiving care at Federal Medical Centre, Jabi Abuja. Using the electronic medical records, key variables of interest were extracted, and the effects of comorbid conditions on Type 2 Diabetes Mellitus (T2DM) were determined. Results The summary results revealed that the incidence of T2DM was approximately 107(66.1%) had T2DM, while about 159 (98.2%) out of the 162 patients with one or more other diseases had T2DM. There were more female patients, 97(59.9%) with cases of DM than male patients. Patients aged 40-69 years have more prevalence cases of DM (73.5%), with those engaging in businesses or trading common in this category (29.63%). Most of these patients had Hypertension as a comorbid condition 110(67.9). The results based on the logistic model showed that patients with concordant comorbid conditions are 2.11 times more likely to develop T2DM. The Bayesian logistic regression model revealed a positive association between gender and comorbidity; the male patients were 1.65 times more likely to develop comorbidity, and patients with a smoking history were 1.56 times more likely to develop comorbidity. T2DM was not associated with systolic blood pressure. Conclusions This present study provides elaborate details on incidences of DM and associated comorbidity conditions in the study area and its environs. A Bayesian model seems to be more accurate than conventional logistic regression based on the present findings. This, in turn, could be used to formulate health policies geared towards effective management, control and prevention of DM of any kind and community sensitization on DM in Nigeria.
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