{"title":"肿瘤细胞与免疫系统竞争的分数阶导数模型","authors":"M. Elkaf, K. Allali","doi":"10.23939/mmc2023.02.288","DOIUrl":null,"url":null,"abstract":"Modeling a dynamics of complex biologic disease such as cancer still present a complex dealing. So, we try in our case to study it by considering the system of normal cells, tumor cells and immune response as mathematical variables structured in fractional-order derivatives equations which express the dynamics of cancer's evolution under immunity of the body. We will analyze the stability of the formulated system at different equilibrium points. Numerical simulations are carried out to get more helpful and specific outcome about the variations of the cancer's dynamics.","PeriodicalId":37156,"journal":{"name":"Mathematical Modeling and Computing","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Fractional derivative model for tumor cells and immune system competition\",\"authors\":\"M. Elkaf, K. Allali\",\"doi\":\"10.23939/mmc2023.02.288\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Modeling a dynamics of complex biologic disease such as cancer still present a complex dealing. So, we try in our case to study it by considering the system of normal cells, tumor cells and immune response as mathematical variables structured in fractional-order derivatives equations which express the dynamics of cancer's evolution under immunity of the body. We will analyze the stability of the formulated system at different equilibrium points. Numerical simulations are carried out to get more helpful and specific outcome about the variations of the cancer's dynamics.\",\"PeriodicalId\":37156,\"journal\":{\"name\":\"Mathematical Modeling and Computing\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mathematical Modeling and Computing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23939/mmc2023.02.288\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical Modeling and Computing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23939/mmc2023.02.288","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Mathematics","Score":null,"Total":0}
Fractional derivative model for tumor cells and immune system competition
Modeling a dynamics of complex biologic disease such as cancer still present a complex dealing. So, we try in our case to study it by considering the system of normal cells, tumor cells and immune response as mathematical variables structured in fractional-order derivatives equations which express the dynamics of cancer's evolution under immunity of the body. We will analyze the stability of the formulated system at different equilibrium points. Numerical simulations are carried out to get more helpful and specific outcome about the variations of the cancer's dynamics.