自然流产胎儿组织:移植研究的新选择?

Fetal therapy Pub Date : 1989-01-01 DOI:10.1159/000263388
E D Thorne, M Michejda
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引用次数: 7

摘要

虽然胎儿组织移植可能会减轻很多痛苦,但目前的政策禁止联邦政府资助使用选择性堕胎组织的研究。使用自然流产的胎儿组织可以避免道德上的担忧。如果现有的小样本研究外推到美国人口,那么每年约有75万名胎儿在第28周自然流产(50万名在妊娠早期,25万名在妊娠中期)。研究人员的共识是,自然流产的胎儿数量很少,不适合移植,因为他们出生时已经死亡或有缺陷。这种直觉可能没有证据支持,迫切需要关注这些问题的研究。
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Fetal tissue from spontaneous abortions: a new alternative for transplantation research?

While transplantation of fetal tissues may alleviate a great deal of suffering, current policy bars federal funding of research using tissue from elective abortions. Using fetal tissue from spontaneous abortions would obviate the moral concerns. If existing studies of small samples are extrapolated to the US population, then each year about 750,000 fetuses are aborted spontaneously by week 28 (500,000 in the first trimester and 250,000 in the second trimester). The consensus among researchers is that spontaneously aborted fetuses are few in number, and inappropriate for transplantation because they are born dead or have defects. This intuition may not be supported by the evidence, and there is a compelling need to focus research on these issues.

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