抗生素对再植牙愈合的影响。狗的实验研究]。

T Lambrianidis, J Molyvdas, K Lyroudia, E Stasinopoulos
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引用次数: 0

摘要

虽然:1 .没有发现因牙齿再植而引起的立即急性感染,2 .牙齿再植后抗生素的使用受到质疑,但通常建议在脱臼牙齿再植时使用抗生素。本实验研究的目的是探讨抗生素对再植牙愈合的影响。对4只5 ~ 7月龄犬的16颗上下颌恒侧切牙即刻进行根管治疗。在实验当天肌肉注射土霉素,在实验期间每天两次给两只狗(8颗牙齿)注射土霉素。处死动物,给予15天和22天的观察期。结果在血红素伊红染色切片中进行组织病理学评估。结果显示,实验组(给予抗生素)的骨吸收腔较浅,没有炎症细胞,而对照组也有炎症细胞。
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[Effect of antibiotic administration on the healing of replanted teeth. Experimental investigation in dogs].

Administration of antibiotics is usually recommended when an avulsed tooth is replanted although: a. no immediate acute infection as a consequence of tooth replantation has been known, b. their administration following tooth replantation has been questioned. The purpose of this experimental study was to investigate the effect of antibiotic administration on the healing of replanted teeth. 16 maxillary and mandibular permanent lateral incisors of four dogs aged from 5 to 7 months were immediately replanted without endodontic treatment. Oxytetracycline was administered intramuscularly the day of the experiment and twice daily through the experimental period in two of the dogs (8 teeth). The animals were sacrificed so as to provide observation periods of 15 and 22 days. Results were evaluated histopathologically in haematoxyline eosine stained sections. Results obtained showed shallower resorptine cavities without inflammatory cells in the experimental group (administration of antibiotics) than those found in the control group where inflammatory cells were also present.

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