[Comparison of carrageenan-induced experimental inflammation in cheek and on dorsum of guinea-pigs].

Carrageenan is a high molecular weight sulfated polygalactose extracted from the marine algae and several biological and immunological properties. Carrageenan granuloma induced subcutaneously in guinea pigs has been widely used in connective tissue studies. Carrageenan is also commonly used as an excellent phylogistic agent for inducing experimental edema. In the present investigation carrageenan granuloma produced on the dorsum of guinea was compared with the inflammatory reaction produced in the cheek. The histopathologic investigations showed that the inflammatory reaction occurred in the buccal tissues was more powerful and the healing manifestations appeared earlier and continued more rapidly in the cheek.