维生素D——北欧营养建议2023的范围审查

IF 3.5 4区 医学 Q2 FOOD SCIENCE & TECHNOLOGY Food & Nutrition Research Pub Date : 2023-11-13 DOI:10.29219/fnr.v67.10230
Magritt Brustad, Haakon E. Meyer
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引用次数: 0

摘要

维生素D是一种必需营养素。它在钙和磷代谢中的作用,以及在健康骨骼的发育和维持中的作用是有据可查的。此外,有证据表明维生素D能适度降低总死亡率和癌症死亡率,但不能降低癌症发病率。维生素D是独一无二的,因为饮食和阳光诱导的皮肤生成都是这种维生素的来源。因此,个人维生素D水平是日晒和饮食摄入量的总和。维生素D受体的发现以及体内许多组织和器官中生物活性维生素D的活化,为维生素D具有骨骼外功能的假说提供了支持。关于维生素D和几种健康结果的科学文献数量众多,并且在过去二十年中呈指数级增长。然而,尽管有大量的科学出版物和研究质量的提高,维生素D补充剂并没有显示出在足够的范围内(即循环25羟维生素D >50 nmol/L)时能带来额外的健康益处。缺乏针对身体不足或缺陷个体的精心设计的研究。 总的证据并不支持维生素D摄入量超过目前的推荐量会对健康产生额外的有益影响。
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Vitamin D – a scoping review for Nordic nutrition recommendations 2023
Vitamin D is an essential nutrient. Its role in calcium and phosphorous metabolism, and in the development and maintenance of a healthy skeleton is well documented. In addition, there is some evidence for vitamin D decreasing total mortality and cancer mortality modestly, but not cancer incidence. Vitamin D is unique, as both diet and sun induced production in skin are sources to this vitamin. Individual vitamin D status is thus a sum of both sun exposure and dietary intakes. The discovery of vitamin D receptors and the activation of biological active vitamin D in numerous tissues and organs in the body has given support to hypothesis on vitamin D having extra-skeletal functions. The scientific literature on vitamin D and several health outcomes is high in numbers and has been increasing exponentially the last two decades. However, despite this large body of scientific publications and improvement in study quality, vitamin D supplementation has not shown to give additional health benefits when status is in sufficient range (i.e. circulating 25 hydroxyvitamin D >50 nmol/L). Well-designed studies on insufficient or deficient individuals are lacking. The totality of evidence does not support that increased intake of vitamin D beyond current recommendation will have additional beneficial health effects.
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来源期刊
Food & Nutrition Research
Food & Nutrition Research FOOD SCIENCE & TECHNOLOGY-NUTRITION & DIETETICS
CiteScore
5.20
自引率
9.10%
发文量
47
审稿时长
14 weeks
期刊介绍: Food & Nutrition Research is a peer-reviewed journal that presents the latest scientific research in various fields focusing on human nutrition. The journal publishes both quantitative and qualitative research papers. Through an Open Access publishing model, Food & Nutrition Research opens an important forum for researchers from academic and private arenas to exchange the latest results from research on human nutrition in a broad sense, both original papers and reviews, including: * Associations and effects of foods and nutrients on health * Dietary patterns and health * Molecular nutrition * Health claims on foods * Nutrition and cognitive functions * Nutritional effects of food composition and processing * Nutrition in developing countries * Animal and in vitro models with clear relevance for human nutrition * Nutrition and the Environment * Food and Nutrition Education * Nutrition and Economics Research papers on food chemistry (focus on chemical composition and analysis of foods) are generally not considered eligible, unless the results have a clear impact on human nutrition. The journal focuses on the different aspects of nutrition for people involved in nutrition research such as Dentists, Dieticians, Medical doctors, Nutritionists, Teachers, Journalists and Manufacturers in the food and pharmaceutical industries.
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