重金属对库尔德斯坦地区石油工业工人肾功能的影响

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引用次数: 0

摘要

重金属严重污染了环境。肾脏通常是第一个受到重金属暴露影响的器官,因为它具有积累和解毒金属离子的潜力。本研究对伊拉克库尔德斯坦地区油田工作人员的一些重金属和肾功能进行了研究。这项研究是基于近五年来收集的原始数据。参与该地区研究的40名成年男性被分为两组;前者包括20名在油田地区接触职业性化学品5年以上的人,后者包括20名未接触职业性化学品的人作为对照组。采用Cobas C311仪器作为生化分析仪检测血清生化指标,采用电感耦合血浆检测全血重金属含量。结果显示,与对照组相比,暴露组中某些重金属(银(Ag)、铁(Fe)、镉(Cd)、锰(Mn)和钒(V))的含量有所增加,差异非常显著。然而,其他重金属(汞(Hg)、铅(Pb)和锌(Zn))的水平在两组之间没有统计学上的显著差异。此外,除尿酸显著升高外,暴露组的肾功能参数水平,包括肌酐和血尿素,与对照组相比均无显著升高。
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Effect of heavy metals on kidney function among petroleum industry workers in the Kurdistan region
Heavy metals have severely polluted the environment. The kidney is usually the first organ to be impacted by heavy metal exposure due to its potential to accumulate and detoxify metal ions. Some heavy metals and kidney function of oil field employees in Kurdistan Region of Iraq were studied in this research. This study was based on primary data collected throughout recent five years. Forty adult males who participated in this region were divided into two main groups; the former consisted of twenty individuals who had been exposed to Occupational Chemicals for more than five years in the oilfield area, and the other included twenty individuals who had not been exposed and used as a control group. Cobas C311 instrument was used as a biochemical analyzer to investigate some biochemical parameters in the serum level, and inductively coupled plasma was performed to estimate some heavy metals in whole blood. The results show a highly significant difference in some heavy metals such as (Silver (Ag), Iron (Fe), Cadmium (Cd), Manganese (Mn) and Vanadium (V)) which increased in the exposed group compared to the group that served as a control. However, there was no statistically significant difference in the levels of the other heavy metals (Mercury (Hg), Lead (Pb), and Zinc (Zn)) between the two groups described. Furthermore, the level of kidney function parameters, including creatinine and blood urea, was revealed non-significantly higher than in the exposed group compared to the control group, except for uric acid, which significantly rose.
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