桡骨角膜切开术后角膜生物力学不稳定的鲍曼层移植

O. G. Oganesyan, P. M. Ashikova, A. V. Ivanova, K. B. Letnikova, C. O. Oganesyan, P. V. Makarov
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引用次数: 0

摘要

放射状角膜切开术(RK)的晚期并发症通常是由角膜生物力学特性的改变引起的。目的:研究RK术后鲍曼层(BL)移植的长期稳定作用。材料和方法。在一项有限的、前瞻性的、单中心的先导研究中,我们对2名年龄分别为60岁和55岁的男性患者(2只眼睛)进行了手术。桡骨切口分别于34年和38年前进行。手术指征为进行性角膜生物力学不稳定和功能性屈光视力波动。术后12个月内评估并发症、矫正视力、角膜测量参数、角膜生物显微透明度和患者满意度。结果。随访期间无并发症发生,角膜及移植物保持透明。BS移植物的平均厚度为20±2.1µm。隐形眼镜矫正后的平均视力由0.4±0.3提高到0.65±0.1,角膜散光平均指标由1.9±1.6提高到3.0 D, 6、9、12个月后这些指标保持不变,说明角膜达到了生物力学稳定性,无屈光-视力波动。结论。在晚期RK并发症中,BS移植部分恢复角膜前表面的正常解剖结构,并在12个月的随访期间确保其生物力学稳定性。为了使结论最大程度地客观,需要在更长的观察期内研究更多的临床病例。
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Transplantation of the Bowman’s layer in cases of biomechanical instability of the cornea after radial keratotomy
Late complications of radial keratotomy (RK), are as a rule caused by a change in the biomechanical properties of the cornea. Purpose : to study the long-term stabilizing effect of the Bowman’s layer (BL) transplantation after RK. Material and methods . In a limited, prospective, monocentric pilot study we operated 2 male patients (2 eyes) aged 60 and 55. The radial incisions had been performed 34 and 38 years ago. The indications for surgery were progressive biomechanical instability of the cornea and functional refractive visual fluctuations. Within 12 months after the operation, complications, corrected visual acuity, keratometric parameters, biomicroscopic transparency of the cornea, and patient satisfaction were assessed. Results. No complications were noted during the follow-up period, the cornea and graft retained transparency. The average thickness of the BS graft was 20±2.1 µm. The average visual acuity corrected by contact lenses increased from 0.4±0.3 to 0.65±0.1, the average indicator of keratometric astigmatism changed from 1.9±1.6 to 3.0 D, these indicators remained after 6, 9 and 12 months, which indicates that biomechanical stability of the cornea was achieved and that the refractive-visual fluctuations are absent. Conclusion . In late term RK complications, BS transplantation partially restores the normal anatomy of the anterior surface of the cornea and ensures its biomechanical stability during a 12-month follow-up period. For the conclusions to be maximally objective, more clinical cases should be studied within a longer observation period.
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CiteScore
0.50
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0.00%
发文量
107
审稿时长
16 weeks
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