大鼠胎儿皮质移植不能避免新生儿运动皮质损伤后的梁行走缺陷。

R S Swenson, E H Danielsen, B S Klausen, E Erlich, J Zimmer, A J Castro
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引用次数: 8

摘要

出生时单侧运动皮质损伤的成年大鼠表现出通过高架窄梁的缺陷。这些缺陷表现为后肢从脊柱边缘滑落,在病变放置后立即将胎儿皮质移植到病变腔内的动物中也不能幸免。
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Deficits in beam-walking after neonatal motor cortical lesions are not spared by fetal cortical transplants in rats.

Adult rats that sustained unilateral motor cortical lesions at birth demonstrated deficits in traversing an elevated narrow beam. These deficits, manifested by hindlimb slips off the edge of the beam, were not spared in animals that received fetal cortical transplants into the lesion cavity immediately after lesion placement.

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