[成人原发性急性腹膜炎]。

D Rădulescu, E Păcescu
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引用次数: 0

摘要

作者报告了12例原发性急性腹膜炎,这些病例是在10年内手术的,占急性腹膜炎病例总数的2.8%,不包括术后腹膜炎病例。因为他们是如此罕见,这是可以理解的,原发性急性腹膜炎的成人不太为人所知的全科医生在外科。这些患者的特殊背景,通常涉及其他形式的病理特征,以及普遍低下的免疫背景,解释了不典型的临床演变,局部腹部征象减弱,这一事实阻碍了诊断,因此治疗。一般来说,成年人到外科来的比较晚,通常是从其他科室(糖尿病、内科、妇科、传染病等)转过来的。外科医生在诊断时也有困难。当决定进行手术时——在大多数情况下,这发生在晚期——腹膜炎通常是化脓性期,需要仔细引流腹膜腔,并应在手术台上应用大剂量抗生素治疗。术前病因诊断困难。腹膜渗出液的直接细菌学检查是决定性的,即使在手术早期也应由外科医生要求。穷尽性内脏手术探查,原则上应消除继发性腹膜炎,在这些患者中,通常是老年,肥胖,有多重干预的情况下,既不容易实施,也没有风险。阑尾切除术,作为补充姿态,是禁忌的。与儿童相比,成人的预后非常严重,围手术期发病率和死亡率非常高(作者的经验超过50%)。
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[Primary acute peritonitis in adults].

The authors report 12 cases of primary acute peritonitis-that were operated over a period of 10 years, representing 2.8% of the total number of acute cases of peritonitis, with the exclusion of cases of postoperative peritonitis. Since they are so rare it is understandable that primary acute peritonitis of the adult are less well known by the general practitioner in surgery. The particular background of these patients, frequently involving other forms of pathologic features, and the generally depressed immunological background explains the atypical clinical evolution, with attenuated local abdominal signs, a fact which retards the diagnosis, and hence the therapy. As a general rule adults come rather late in surgical departments, usually transferred from another department (diabetes, internal medicine, gynecology, communicable diseases, etc.). The surgeon also has difficulties in making a diagnosis. When the decision to operate has been taken--in most of the cases this happens at a late stage-peritonitis is usually is the purulent phase and careful drainage of the peritoneal cavity is necessary, associated to antibiotherapy that should be applied on the surgical table, and with massive doses. Preoperative etiological diagnosis is difficult. Direct bacterioscopy of the peritoneal exudate is decisive and it should be asked for by the surgeon even in the early stage of surgery. Exhaustive visceral surgical exploration, which should, in principle, eliminate secondary peritonitis is neither easy to perform, nor without risks in these patients, usually aged, obese, with multiple interventions in antecedents. Appendectomy, as a complementary gesture, is contraindicated. The prognosis in the adult, in contrast with that of children, is severe, with very high perioperative morbidity and mortality (above 50% in the authors' experience).

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