[左、右结肠癌的临床进展与治疗比较]。

S Constantinoiu, P Papahagi, D Peţa, I Niculescu, C Agache, I N Mateş
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引用次数: 0

摘要

本文报道了“Griviţa”临床医院外科门诊21年来(1966-1986)大肠癌的临床特点,重点报道了左、右结肠的位置特点。而左结肠癌(LCC)的32%的病例开始于闭下综合征和闭塞综合征,对治疗和预后有特殊影响,在右结肠癌(RCC)只有3.5%的病例诊断建立在闭下综合征阶段。在手术过程中,57%的LCC患者出现了转移性腺病,而只有37%的RCC患者出现了转移性腺病,17.7%的LCC患者出现了肝转移,10.9%的RCC患者出现了肝转移。12%的小细胞癌患者术后立即死亡,而只有9.3%的小细胞癌患者术后立即死亡。在研究期间的最后10年,患者定期再次入院,重新调查,并应用5-氟尿嘧啶单化疗序贯治疗。在最后一个时期,55例RCC患者的5年生存率为25例(45.4%),109例LCC患者的5年生存率为41例(37.6%)。
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[Comparative clinico-evolutive and therapeutic aspects in cancer of the right and left colon].

The paper reports on the casuistics of the colon cancer in the Clinic of Surgery of the "Griviţa" Clinical Hospital, for 21 years (1966-1986) with emphasis on the situs peculiarities on the right and left colon. Whereas the left colon cancer (LCC) started in 32% of cases with subocclusive and occlusive syndromes having special implications on the treatment and prognosis, in the right colon cancer (RCC) only in 3.5% of cases the diagnosis was established in the stage of subocclusive syndrome. During surgery the metastatic adenopathy was met in 57% in LCC and only in 37% in RCC, and the hepatic metastases in 17.7% in LCC and in 10.9% in the RCC cases. The immediate postsurgery mortality was present in 12% of the LCC cases and in only 9.3% of the RCC cases. In the last 10 years of the period studied, the patients were periodically readmitted into the hospital, reinvestigated, and monochemotherapy with 5-fluorouracil was applied in sequential cures. In this last period, the survival at 5 years was of 25 (45.4%) in the 55 patients operated for RCC and of 41 (37.6%) in the 109 patients operated for LCC.

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