母婴细菌感染

M.-H. Blond (Praticien hospitalier, pédiatre) , P. Poulain (Professeur des Universités, praticien hospitalier, gynécologue-obstétricien) , F. Gold (Professeur des Universités, praticien hospitalier, pédiatre) , E. Bingen (Professeur des Universités, praticien hospitalier, microbiologiste) , H. Watier (Professeur des Universités, praticien hospitalier, immunologiste) , R. Quentin (Professeur des Universités, praticien hospitalier, microbiologiste)
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引用次数: 0

摘要

在过去十年中,针对maternal-fœtal污染引起的新生儿细菌感染的频率和严重程度,提出了许多建议。它们的主要目的是促进无乳链球菌的筛查,并通过产前抗生素治疗消除它。在这篇文献综述中,我们试图综合法国和美国相继发表的建议,重点关注相关的缺点:应用困难,与抗生素治疗相关的孕产妇风险,即耐药革兰氏菌的出现,新生儿风险,因为这些策略的结果表明它们可能无效(细菌耐药新生儿感染的爆发,败血症的发作,使用更广泛的抗生素治疗,以及细菌耐药医院感染率的增加)。最后,我们将考虑感染风险的因素,并提出一些类型的管理。
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Infection bactérienne maternofœtale

Numerous recommendations have been addressed this past decade in relation with the frequency and severity of bacterial infections of the newborn induced by maternal-fœtal contamination. They are principally aimed at promoting the Streptococcus agalactiae screening and its eradication by a per partum antibiotherapy. In this literature review we attempt to present a synthesis of the successive published French and American recommendations, with a focus on the related drawbacks: difficulty of application, maternal risk in relation with the antibiotherapy, i.e., the emergence of resistant Gram–bacteria, the neonatal risk, since the results of these strategies suggest their likeliness to be inefficacious (outbreak of bacteria-resistant neonatal infections, sepsis onset, use of antibiotherapies with wider spectrum, and increased rate of bacteria-resistant nosocomial infections). Finally we will consider the factors involved in the risk of infection, and propose some types of management.

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