胆汁分泌。从外科角度看高胆固醇血症的意义[j]。

A Díez Cascón, V Zanón Navarro, E Díez-Cascón Menéndez, V Ayuso Osuna, A Muñoz González
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引用次数: 0

摘要

在进行Kehr管胆总管造口术的患者中,外科医生可能会观察到,但很少,严重的晚期慢性肝病或持续性胆汁淤积的患者出现非胆汁酸依赖性的重要高胆汁血症。每天流出体外的胆汁量可达两升甚至更多。我们在两例代偿性肝病患者和另一例由胆总管结石引起的轻度胆汁淤积患者中观察到这一点。我们也在另外三个肝脏和主要胆道完全正常的人身上发现了同样的情况。这种高胆固醇是持续的,并随着食物的摄入而迅速增加。这种增加与胃肠道激素有关,特别是分泌素,当胃食糜部分进入十二指肠时产生分泌素。
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[Biliary secretion. Significance of hypercholeresis from the surgical point of view].

In patients carrying a Kehr tube choledochostomy, the surgeon may observe, but rarely, important hypercholeresis, non-bile-acid dependent, in people with severe advanced chronic hepatic diseases or persistent cholestasis. The amount of bile flowing to the outside can reach two liters and more daily. We have seen this in two patients with compensated hepatic disorders and in another suffering from light cholestasis produced by choledocholithiasis. We have also found the same in three other people with liver and the main biliary extrahepatic tract completely normal. This hypercholeresis is continuous and subject to rapid increases relative to the ingestion of food. Such increases are related to gastrointestinal hormones, specially secretin, which is produced when portions of gastric chyme enters the duodenum.

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