阿莫西林在治疗肺炎和急性支气管炎中的应用

Pharmatherapeutica Pub Date : 1989-01-01
D Ekoule
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引用次数: 0

摘要

采用口服和/或肠外注射阿莫西林治疗52例中重度至重度支气管炎、支气管肺炎或急性大叶性肺炎的青年和成人患者。从发病到开始治疗的平均时间为3.8天。根据病情的严重程度,患者每天接受2至3次阿莫西林的剂量,从375毫克到1克不等,平均持续6.4天。3天后,除3例患者外,其余患者发热、咳嗽、胸膜痛等临床症状均完全消失。77%的患者反应优异或良好,14%的患者满意。8例患者报告了轻至中度副作用,如荨麻疹和恶心,但严重程度不足以中断治疗。总的来说,阿莫西林被认为对82%的患者有效,对11%的患者部分有效。
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[Oral and parenteral amoxicillin in the treatment of pneumonia and acute bronchitis].

Oral and/or parenteral amoxycillin was used to treat 52 young and adult patients suffering from moderately severe to severe bronchitis, bronchopneumonia or acute lobar pneumonia. The mean time between onset of disease and start of treatment was 3.8 days. Patients received doses of amoxycillin ranging from 375 mg to 1 g 2 to 3-times daily depending on the severity of the condition for a mean of 6.4 days. There was complete resolution of clinical symptoms such as fever, cough and pleural pain after 3 days in all but 3 of the patients. Response was considered excellent or good in 77% of patients and satisfactory in 14%. Mild to moderate side-effects such as urticaria and nausea were reported in 8 patients but were not severe enough to interrupt treatment. Overall, amoxycillin was considered to be effective in 82% and partially so in 11% of the patients treated.

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