[高海拔居民和慢性高原反应患者的精子数量和精子生物化学]。

M A García-Hjarles
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摘要

对9名来自海平面(150米)、年龄19-32岁的健康成年男性和15名来自高海拔(NA)、9名来自Cerro de Pasco(4300米)和6名来自Morococha(4540米)、年龄19-45岁的健康男性进行了精液分析研究。对5例年龄23 ~ 52岁的慢性高原病(MMC)患者进行了研究。NA和MMC的体积和运动性相似,但均低于海平面受试者,但仍在正常范围内;每ml精子数量在海平面上低于NA和MMC,但由于精液体积较大,海平面上精子总数较高。海面上的果糖为356 +/- 53 mg/100 ml(平均+/- S.E.),与NA 237 +/- 45相似,而MMC显著低于NA 237 +/- 60。柠檬酸在海平面处低于NA和MMC。Na、K和Cl在三组间相似。MMC中较低浓度的果糖与这些组中已经发现的睾丸功能下降相似。然而,值得指出的是,生育能力在所有群体中都得到了保留。MMC的正常生殖功能与此过程是由于环境不适应而发生的概念相反。
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[Sperm count and seminal biochemistry of high altitude inhabitants and patients with chronic altitude sickness].

Semen analysis has been studied in 9 healthy adult males from sea level (150 m), age 19-32 years old and 15 healthy males from high altitude (NA), 9 from Cerro de Pasco (4,300 m) and 6 from Morococha (4,540 m), ages 19-45 years old. Five patients with chronic mountain sickness (MMC), whose ages ranged from 23 to 52 years old were also studied. The volume and motility were similar in NA and MMC, however both were below than in sea level subjects, but still in the normal range; the number of spermatozoa per 1 ml was lower at sea level than in NA and MMC, although the total number was higher at sea level due to the higher semen volume. Fructose at sea level was 356 +/- 53 mg/100 ml (mean +/- S.E.) which is similar to NA 237 +/- 45 whereas a MMC was significantly lower, 142 +/- 60. Citric acid was lower at sea level than in NA and MMC. Na, K and Cl, were similar among the three groups. The lower concentration of fructose in MMC parallels the decreased testicular function already found in these groups. However it is worthy to point out that the fertility is preserved in all the groups. The normal reproductive function in MMC is against the concept that this process occurs as a consequence of environmental disadaptation.

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