卵巢上皮性肿瘤的预后因素。

L Frigerio, A Ferrari, L Busci, A Pirondini, S Garsia, M Caldarella, G Pifarotti
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摘要

本文对1975年至1986年间87例上皮性卵巢癌患者进行了集中评估。在所有病例中,原手术后进行手术再评估,以评估辅助治疗的效果,并研究无明显疾病的病例。经Kaplan-Meier计算,3年后精算生存率显示,复查阴性患者的生存率为73.5%,复查阳性患者的生存率为32% (P < 0.01)。手术复查及组织学检查阴性34例(39%)。肿瘤的早期分期、组织型、组织学分级、腹膜冲洗和患者年龄是评估肿瘤预后的重要因素。70.8%的女性首次手术时无肿瘤残留(RT),辅助治疗后完全缓解,而RT大于2 cm的女性为25.8% (P < 0.01)。二次复查阴性是评估上皮性卵巢癌最重要的预后因素(P < 0.001)。
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[Prognosis factors in epithelial tumors of the ovary].

87 patients treated for epithelial ovarian carcinoma between 1975 and 1986 were evaluated intensively. In all cases the original operation was followed by surgical reassessment to evaluate the result of adjuvant therapy and to study the cases without apparent disease. The actuarial survival rate after 3 years, by Kaplan-Meier calculation, demonstrated 73.5% survival in patients with negative second-look versus 32% in presence of positive reassessment (P less than 0.01). Surgical reexploration and histologic study were negative in 34 cases (39%). Original stage, histotype, histological grading, peritoneal washing and age of patients were considered for prognostic evaluation of the tumor. The absence of residual tumor (RT) at first surgery resulted in complete response after adjuvant therapy in 70.8% of women, versus 25.8% with RT greater than 2 cm (P less than 0.01). Negative second-look appears the most important prognostic factor for the evaluation of epithelial ovarian cancer (P less than 0.001).

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