A Roth, D Klein, F Paccolat, D Hermès, M Pelizzone, J L Mandel, R Feil
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引用次数: 0
摘要
1986年和1987年对丈夫为protanope,妻子为deuteranope (Franceschetti, 1949)夫妇的后代(3代)进行了检查。这对夫妇有4个孩子,其中3个儿子是德国人,1个女儿是双携带者,表型正常。这个女孩,反过来,以典型的方式,有三个孩子:一个女儿,是简单的携带者,是典型的正常,一个儿子是蛋白质和一个儿子是多变性。对3名正常人的基因组DNA的研究发现,存在两个负责绿色的基因和一个负责红色的基因;一名原异形动物的基因组DNA显示出红色基因的修饰,而两名后蜥蜴的基因组DNA显示出绿色基因的缺失。第二对夫妇的后裔,丈夫是deuteranope,妻子是protanope (Franceschetti and Klein, 1956),完全是女性。因此,它只包括表型正常的人。
[The progeny of the two protan and deutan families described by Franceschetti and Klein (1949, 1956), one generation later. Genealogy, color vision and genomic DNA].
The progeny of the couple of which the husband was protanope and the wife deuteranope (Franceschetti, 1949) has been examined (3 generations) in 1986 and 1987. This couple had 4 children, of which 3 sons are deutan and 1 daughter, a double carrier, is phenotypically normal. This girl, in her turn and in exemplary fashion, has 3 children: 1 daughter, being simple carrier, is phenotypically normal, 1 son is protan and 1 son deutan. The study of the genomic DNA of 3 normal subjects reveals the presence of two genes responsible for green and one gene responsible for red; the genomic DNA of a protanomalous subject shows a modification of the gene for red, while that of two deuteranopes shows absence of genes responsible for green. The descent of the second couple in which the husband was deuteranope and the wife protanope (Franceschetti and Klein, 1956) is exclusively of female sex. Therefore it comprises only phenotypically normal persons.