[止汗剂和除臭剂——成分和评价]。

V A Lukacs, H C Korting
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引用次数: 0

摘要

抗蒸腾剂和除臭剂越来越受到人们的关注。水合氯铝和四氯水合锆铝甘氨酸络合物是当今商业抗蒸腾剂中最常用的活性成分。氯化铝和抗胆碱能物质溴化丙烷是重要的替代品,尽管不太常见。除臭剂的有效成分主要是香水或杀菌/抑菌物质,如三氯生。此外,还有一些物质可以抑制难闻的气味(如蓖麻油酸锌)或影响皮肤表面的pH值(如柠檬酸三乙酯)。就像化妆品行业一般,产品的安全性和有效性是实验和临床评估的主要参数。功效的确定是基于在模型情况下的嗅觉测试以及对相关效应(例如对皮肤微生物群的影响)的检测。
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[Antiperspirants and deodorants--ingredients and evaluation].

Antitranspirants and deodorants gain more and more interest. Aluminium chlorohydrate and aluminium zirkonium tetrachlorohydrate glycine complex are the most frequently used active ingredients in commercial antitranspirants today. Aluminium chloride and propantheline bromide, the anticholinergic substance, are important alternatives although less common. Active ingredients of deodorants are mainly perfumes or bactericidal/bacteriostatic substances, such as triclosan. In addition, there are substances which are meant to bind offending smells (e.g. zinc ricinoleate) or to influence the skin surface pH (e.g. triethyl citrate). As in the cosmetics industry in general, both safety and efficacy of a product are major parameters in the experimental and clinical evaluation. Establishment of efficacy is based on olfactory tests in model situations as well as on the detection of associated effects (e.g. influence on cutaneous microflora).

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