[寄生虫密度在恶性疟疾临床表现中的作用和现状]。

J E Touze, H Chaudet, A Bourgeade, B Faugère, P Hovette, P Aubry, P Pène
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引用次数: 0

摘要

1987年共发现56例恶性疟原虫携带者,其中男47例,女9例,平均年龄32岁。临床观察:恶性疟35例,低寄生虫血症(小于1000 HPM)疟5例,热带脾肿大综合征3例,孤立性双、三红细胞减少症10例,脑型疟1例,无症状感染者2例。从统计学上看,寄生虫血症与发热、脾肿大、Hb水平、血小板计数等临床及生物学症状无显著相关性。然而,我们注意到急性疟疾(恶性疟疾和脑型疟疾)的寄生虫血症水平高于非典型形式(慢性内脏疟疾、血液病)。所有代表“疟疾感染”的无症状携带者均表现为低寄生虫血症(低于1,000 HPM)。
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[Current clinical aspects and role of parasitic density in the manifestations of falciparum malaria].

56 patients carriers of Plasmodium falciparum were observed throughout 1987: 47 males and 9 females of a mean age of 32. The following clinical aspects were observed: Falciparum malaria: 35 cases, malaria with a low parasitaemia (less than 1,000 HPM): 5 cases, tropical splenomegaly syndrome: 3 cases, isolated bi- or tricytopenia: 10 cases, cerebral malaria: 1 case, asymptomatic carriers: 2 cases. Statistically speaking, no significant correlation was observed between parasitaemia and the following clinical and biological symptoms: fever, splenomegaly, Hb level, platelet count. However, we noted a level of parasitaemia higher in the acute forms of malaria (Falciparum malaria and cerebral malaria) than in the non typical forms (chronic visceral malaria, haematological disorders). All asymptomatic carriers, who represent "malaria infection", presented a low parasitaemia (less than 1,000 HPM).

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