高血压患者的下尿路症状。心血管风险及其对生活质量的影响]。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-10-01 DOI:10.1016/j.hipert.2023.05.008
M. Diosdado-Figueiredo
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引用次数: 0

摘要

目的:了解高血压患者勃起性下尿路症状的患病率、心血管风险及其对生活质量的影响。材料和方法:地点:卫生中心(Vilagarcia, Pontevedra)。时间:2015年4月- 2017年6月。纳入标准:知情同意的高血压患者。测量方法:社会人口学变量、有毒习惯、合并症、血压、心血管风险、分析和检查参数。调查问卷:国际前列腺症状量表(IPSS)、国际勃起功能指数(IIEF-15)和动脉高血压患者的生活质量(MINICHAL)。样本量:n=262(±6%准确度,95%置信度)。统计分析:双变量和多变量统计分析。结果:患者平均年龄65.84岁(12.70岁),平均高血压病程13.25年(9.84年)。76.7%报告有下尿路症状,91.6%为轻度。双变量分析显示与以下变量相关:年龄、教育水平、职业、工作活动、吸烟、良性前列腺肥大、诊断年限、伴随用药、Framingham-Wilson评分、心电图、糖化血红蛋白、肾小球滤过(crocroft - gault)、ldl -胆固醇、身体表现(MINICHAL)、勃起功能障碍。多因素分析显示:腹部肥胖、病理性心电图、Framingham-Wilson评分高风险、勃起功能障碍、使用降尿酸药物会增加风险,不吸烟和使用利尿剂会降低风险。结论:根据Framingham-Wilson评分,四分之三的高血压男性出现下尿路症状,增加了早期心血管疾病的风险。其他预测因素有:腹部肥胖、吸烟、病理性心电图、高Framingham-Wilson评分、勃起功能障碍、使用降尿酸药物。
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Síntomas del tracto urinario inferior en pacientes con hipertensión arterial. Riesgo cardiovascular e impacto en su calidad de vida

Objetives

To determine the prevalence of erectile lower urinary tract symptoms in hypertensive patients, cardiovascular risk and the impact on quality of life.

Material and methods

Setting: Health Center (Vilagarcia, Pontevedra).

Period: April 2015-June 2017.

Inclusion criteria: Hypertensive patient with informed consent.

Measurements

sociodemographic variables, toxic habits, comorbidity, blood pressure, cardiovascular risk, analytical and examination parameters. Questionaries: International Prostate Symptom Scale (IPSS), International Index of Erectile Function (IIEF-15) and quality of life in arterial hypertension (MINICHAL).

Sample size: n = 262 (± 6% accuracy, 95% confidence).

Statistical analysis: Bivariate and multivariate statistical analysis.

Informed consent and ethics committee approval were obtained (2024/237)

Results

The mean age was 65.84 (12.70), and mean hypertension duration of 13.25 (9.84) years. 76.7% reported lower tract urinary symptoms, 91.6% being mild. The bivariate analysis showed an association with the variables: age, educational level, profession, work activity, tobacco, benign prostatic hypertrophy, years of diagnosis, concomitant medication, Framingham-Wilson score, electrocardiogram, glycated hemoglobin, glomerular filtration (Crockroft-Gault), LDL-cholesterol, somatic manifestations (MINICHAL), erectile dysfunction. The multivariate analysis showed increased risk with:abdominal obesity, pathological electrocardiogram, high risk of Framingham-Wilson score, erectile dysfunction, use of hypouricemics agents and decreased with not smoking and use diuretics.

Conclusions

Three quarters of hypertensive men presented lower urinary tract symptoms, increasing the risk of cardiovascular disease early according to the Framingham-Wilson score. Other predictive factors were: abdominal obesity, tobacco, pathological electrocardiogram, high Framingham-Wilson score, erectile dysfunction, use of hypouricemics agents.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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