避孕和性传播感染

Judith Stephenson
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摘要

这一贡献考虑了不同避孕方法与获得性传播感染风险之间的联系。这是一个重大的公共卫生问题,因为性传播感染造成巨大的疾病负担,对妇女的影响尤为严重。全世界每年有3.4亿15 - 49岁的可治愈性传播感染新病例。在发展中国家,性传播感染,甚至不包括艾滋病毒,是仅次于产妇因素的导致疾病、死亡和生命丧失的原因。人们特别关注激素避孕与性传播感染之间的假定联系。然而,对假定的联系进行调查所面临的方法问题是可怕的。这些问题包括混淆性行为和选择避孕药具、选择适当的对照组,以及缺乏对艾滋病毒/性传播感染暴露水平和其他风险因素的精确测量。目前的情况可以总结如下。采用屏障避孕方法大大降低了感染艾滋病毒/性传播感染的风险。激素避孕是一种广泛使用、安全、高效的预防意外怀孕的方法。它与艾滋病毒/性传播感染的关系仍不确定。在缺乏更好证据的情况下,目前推广激素避孕的方法应该继续下去。无论是否使用其他避孕方法,都应强调一贯使用避孕套预防艾滋病毒/性传播感染的重要性和有效性。未来的避孕研究应侧重于预防艾滋病毒/性传播感染和意外怀孕的双重目标。
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Contraception and sexually transmitted infections

This contribution considers links between different methods of contraception and the risk of acquiring sexually transmitted infections (STIs). This is a major public health issue, because STIs cause a huge disease burden that affects women disproportionately. Worldwide each year, there are 340 million new cases of curable STIs in 15–49-year-olds. In developing countries, STIs, even excluding HIV, are second only to maternal factors as causes of disease, death and life lost. There is particular concern about a putative link between hormonal contraception and STIs. However, the methodological problems facing investigation of a putative link are formidable. They include confounding between sexual behaviour and choice of contraceptive, choice of appropriate control group, and lack of precise measures of level of HIV/STI exposure and other risk factors. The current situation can be summarized as follows. The risk of acquiring HIV/STIs is substatially reduced by barrier methods of contraception. Hormonal contraception is a widely used, safe and highly effective method of preventing unintended pregnancy. Its relationship to HIV/STI transmission remains uncertain. In the absence of better evidence, current approaches to promoting hormonal contraception should continue. The importance and effectiveness of consistent condom use to protect against HIV/STI should be stressed, regardless of whether other contraceptive methods are being used. Future contraceptive research should focus on the dual goal of protection against HIV/STIs and unintended pregnancy.

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