提高2000秒/mm2 DWI b值对直肠癌准确定性和定量评估的效果。

IF 1.1 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Arab Journal of Gastroenterology Pub Date : 2023-11-01 DOI:10.1016/j.ajg.2023.09.001
Zhihua Lu , Kaijian Xia , Heng Jiang , Xiaoyan Weng , Mei Wu
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引用次数: 0

摘要

背景和研究目的:更高的b值弥散加权成像(DWI)可以改善癌组织和非癌组织的对比。表观扩散系数-直方图分析是一种能够提供肿瘤异质性统计数据和定量信息的方法。本研究旨在比较两种高b值(1000和2000 sec/mm2) DWI对肿瘤的检测和对早期肿瘤直肠癌的诊断性能。患者和方法:本研究采用盲法和盲法回顾性研究,共纳入56例直肠癌患者和45例患者。两名放射科医师评估ADC评估直方图的定性检测参数和定量参数,并比较两个DWI序列(1000秒/mm2和2000秒/mm2的b值)。特征曲线用于评估ADC直方图在鉴别早期肿瘤中的诊断作用。结果:2000秒/mm2 DWI的b值与1000秒/mm2的b值相比,auc、灵敏度、特异度、精密度显著提高,假阳性率显著降低(p值显著高于≥II期(p = 0.036II和0.016),2000秒/mm2 b值的第5、第10、第5、第10和第25个ADC百分位数的平均ADC (p = 0.031、0.014、0.035和0.025)。在2000秒/mm2 DWI下,两名读者在诊断Ⅰ期肿瘤时,第5百分位ADC的b值auc最高(0.732和0.751)。结论:2000秒/mm2 DWI b值可提高直肠癌的准确检出率。在2000秒/mm2秒/mm2 DWI的b值下,第五个百分位ADC比1000秒/mm2 DWI的b值对早期诊断更有用。
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Improved effects of the b-value for 2000 sec/mm2 DWI on an accurate qualitative and quantitative assessment of rectal cancer

Background and study objectives

A higher b-value Diffusion-weighted imaging (DWI) would improve the contrast between cancerous and noncancerous tissue. Apparent diffusion coefficient (ADC)-histogram analysis is a method that can provide statistical data and quantitative information on tumor heterogeneity. This study aimed to compare two high b-values (1000 and 2000 sec/mm2) DWI in tumor detection and diagnostic performance in identifying early-stage tumor rectal cancer.

Patients and methods

This blinded and blinded retrospective study involved 56 patients with rectal cancer and 45 patients. Two radiologists evaluated the qualitative detection parameters and quantitative parameters of the ADC evaluated histogram and compared them between two DWI sequences (b-value for 1000 sec/mm2 and 2000 sec/mm2). The characteristic curves were used to assess diagnostic administration for the ADC histogram in discriminating early-stage tumors.

Results

The b-value for 2000 sec/mm2 DWI significantly improved AUCs, sensitivity, specificity, and precision and decreased false-positive rate for detection compared to the b-value for 1000 sec/mm2 (p < 0.05). The mean and fifth percentile ADC value for stage I using the b-value for 1000 sec/mm2 DWI was significantly higher than stage ≥ II (p = 0.036II and 0.016 respectively), as the well as fifth, 10th, mean ADC of the fifth, 10th, and 25th ADC percentile at b-value for 2000 sec/mm2 (p = 0.031, 0.014, 0.035 and 0.025 respectively). The AUCs of the fifth percentile ADC at b-value for 2000 sec/mm2 DWI in both readers in differentiating the stage Ⅰ tumor were the highest (0.732 and 0.751).

Conclusion

The b-value for 2000 sec/mm2 DWI could improve the accurate detection of rectal cancer. The fifth percentile ADC at b-value for 2000 sec/mm2 sec/mm2 DWI was more useful for discriminating early stage than the b-value for 1000 sec/mm2 DWI.

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来源期刊
Arab Journal of Gastroenterology
Arab Journal of Gastroenterology Medicine-Gastroenterology
CiteScore
2.70
自引率
0.00%
发文量
52
期刊介绍: Arab Journal of Gastroenterology (AJG) publishes different studies related to the digestive system. It aims to be the foremost scientific peer reviewed journal encompassing diverse studies related to the digestive system and its disorders, and serving the Pan-Arab and wider community working on gastrointestinal disorders.
期刊最新文献
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