【钙化病变的冠状动脉碎石术:钙碎片化】。

Gustavo Inzunza-Cervantes, Erick Alfonso García-Fajardo, Francisco Antonio Martínez-Hernández, Verónica Zazueta-Armenta, Jesús Omar Hernandez-Marquez, Juan Ramón Herrera-Gavilanes
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引用次数: 0

摘要

背景:复杂钙化的冠状动脉病变是经皮冠状动脉介入治疗中经常发现的,几十年来,由于血管造影结果不理想,尽管采用了多种策略,如使用切割球囊、高压球囊或旋转或眶动脉粥样硬化切除术,但围手术期并发症和长期不良事件的发生率高,对有血运重建指征的患者构成了挑战和限制。干预措施的局限性阻碍了其常规应用,最近一种新的斑块修饰技术,即冠状动脉血管内碎石术,已经进入了这种复杂实体的治疗中,该技术包括使用一种特殊改良的球囊来发射脉冲机械能(声压波),从而可以修饰钙化板。临床病例:通过介绍一系列临床病例和回顾文献,我们提出了初步经验,总结和讨论了理解这种新的干预技术对决策所必需的关键因素。结论:冠状动脉血管内碎石术是一种很有前途的技术,可以通过微骨折对冠状动脉浅层和深部钙化病变进行修复和准备,允许支架的放置和有效扩张,根据不同的试验(Disrupt CAD系列,SOLSTICE试验)和记录,该策略显示出高效率和良好的安全性,数据与我们的初步经验一致。
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[Coronary lithotripsy in calcified lesions: fragmented calcium].

Background: Complex calcified coronary lesions are a frequent finding during percutaneous coronary intervention, representing for decades a challenge and limitation in patients with indication of revascularization, due to suboptimal angiographic results, high incidence of perioperative complications and long-term adverse events despite the multiple strategies employed, such as the use of cutting balloon, high-pressure balloons or rotational or orbital atherectomy, interventions with limitations that have hindered its routine use, recently a new plaque modification technique known as coronary intravascular lithotripsy has burst into the treatment of this complex entity, which consists in the use of a specially modified balloon for the emission of pulsatile mechanical energy (sonic pressure waves) that allows modifying the calcified plate.

Clinical case: By presenting a series of clinical cases and reviewing the literature, our initial experience is presented, key elements are summarized and discussed in the understanding of this new intervention technique necessary for decision making.

Conclusion: Coronary intravascular lithotripsy is projected as a promising technique for the modification and preparation of superficial and deep calcified coronary lesions, through microfractures that allow the apposition and effective expansion of the stent, strategy that according to different trials (Disrupt CAD series, SOLSTICE assay) and records presents a high efficiency and good safety profile, data consistent with our initial experience.

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