戈舍林治疗多形性大羊膜红斑1例。

IF 0.7 Q4 ENDOCRINOLOGY & METABOLISM Endocrinology, Diabetes and Metabolism Case Reports Pub Date : 2023-11-23 Print Date: 2023-10-01 DOI:10.1530/EDM-23-0030
Lauren T Tyack, Bronwyn G A Stuckey, John P Walsh
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引用次数: 0

摘要

摘要:我们报告一位46岁女性的多形性大羊膜红斑。她成功地接受了戈舍瑞林(一种GnRH激动剂)的治疗,直到预期的绝经年龄;然而,它的治疗效果持续的时间比预期的要长,可能是由于在脂肪组织中的积累。学习要点:一组与月经周期相关的皮肤病和过敏综合征存在,但在文献中很少报道。绝经前女性皮肤复发的历史应考虑到月经周期。月经周期相关皮肤病的诊断主要是临床诊断,尽管激发试验可以提供帮助。治疗选择很广泛,旨在降低免疫反应和/或抑制排卵。戈舍瑞林可能积累并具有比预期更长时间的促性腺激素抑制作用。
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A case of catamenial erythema multiforme major successfully treated with goserelin.

Summary: We report a case of catamenial erythema multiforme major in a 46-year-old female. She was treated successfully with goserelin, a GnRH agonist, until the expected age of menopause; however, its therapeutic effects persisted for longer than expected, possibly due to accumulation in adipose tissue.

Learning points: A group of menstrual cycle-related dermatoses and hypersensitivity syndromes exist but are rarely reported in the literature. A history of recurrent cutaneous eruptions in premenopausal females should be considered in the context of the menstrual cycle. The diagnosis of menstrual cycle-related dermatoses is largely clinical, although provocation testing can assist. Treatment options are broad and are aimed at reducing the immune response and/or suppressing ovulation. Goserelin may accumulate and have a gonadotrophin-suppressing effect for longer than expected.

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来源期刊
CiteScore
1.50
自引率
0.00%
发文量
142
审稿时长
9 weeks
期刊介绍: Endocrinology, Diabetes & Metabolism Case Reports publishes case reports on common and rare conditions in all areas of clinical endocrinology, diabetes and metabolism. Articles should include clear learning points which readers can use to inform medical education or clinical practice. The types of cases of interest to Endocrinology, Diabetes & Metabolism Case Reports include: -Insight into disease pathogenesis or mechanism of therapy - Novel diagnostic procedure - Novel treatment - Unique/unexpected symptoms or presentations of a disease - New disease or syndrome: presentations/diagnosis/management - Unusual effects of medical treatment - Error in diagnosis/pitfalls and caveats
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