冠状动脉搭桥术后健康相关生活质量改善:1年随访研究

IF 1.2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Scandinavian Cardiovascular Journal Pub Date : 2023-12-01 Epub Date: 2023-11-27 DOI:10.1080/14017431.2023.2284083
Laura Hämäläinen, Mika Kohonen, Jari Laurikka
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引用次数: 0

摘要

目的:本研究的目的是检测冠状动脉旁路移植术(CABG)术后一年内生活质量的变化,并确定可能与这种变化相关的预测因素。设计:2013年至2018年间,采用EQ-5D VAS问卷评估生活质量,对501例患者进行单中心前瞻性研究。患者术前、术后6个月和12个月分别填写问卷。采用单变量和多变量logistic回归分析,确定某些预选因素或EQ5D维度是否对观察到的EQ VAS评分有独立影响。结果:6个月和12个月时EQ- 5d各维度和EQ VAS评分的生活质量均有改善,报告问题数量变化最大的是“活动能力”维度(-34.2%,pp=.001)和“疼痛或不适”维度(-31.0%,p)。结论:以EQ5D维度和相关的整体自评健康(VAS)来判断CABG手术可改善患者的生活质量。这种改善在术后6个月和12个月均可观察到。除LVEF外,我们检查的其他患者特异性风险因素似乎并不影响长期生活质量。
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Health-related quality of life is improved after coronary artery bypass graft surgery: a 1-year follow-up study.

Objectives: The purpose of this study was to detect changes in QoL after coronary artery bypass grafting surgeries (CABG) in one year, and to identify the possible predictive factors associated with the change.

Design: A single-center prospective study of 501 patients was conducted between 2013 and 2018 using the EQ-5D VAS questionnaire for estimating the QoL. The patients filled in a questionnaire preoperatively, at 6 and at 12 months postoperatively. Univariate and multivariable logistic regression analyses were used to find out if certain pre-selected factors or EQ5D dimensions had independent effects on the observed EQ VAS scores.

Results: QoL improved in all EQ-5D dimensions and in EQ VAS scores at 6 and at 12 months: the greatest changes in the number of reported problems were in the dimensions "mobility" (-34.2%, p<.001), "self-care" (-36.7%, p=.001) and "pain or discomfort" (-31.0%, p<.001). With the multivariable regression model, we could show that normal left ventricle ejection fraction (LVEF) and improvement in mobility and pain/discomfort dimensions were in association with improvement of EQ VAS score at 6 months. At 12 months this association was no longer detectable.

Conclusions: CABG procedure can improve patient's QoL when judged with EQ5D dimensions and related overall self-rated health (VAS). This improvement was seen both at 6 and at 12 months postoperatively. Except for LVEF, the other patient-specific risk factors we examined did not seem to affect QoL in the long term.

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来源期刊
Scandinavian Cardiovascular Journal
Scandinavian Cardiovascular Journal 医学-心血管系统
CiteScore
3.40
自引率
0.00%
发文量
56
审稿时长
6-12 weeks
期刊介绍: The principal aim of Scandinavian Cardiovascular Journal is to promote cardiovascular research that crosses the borders between disciplines. The journal is a forum for the entire field of cardiovascular research, basic and clinical including: • Cardiology - Interventional and non-invasive • Cardiovascular epidemiology • Cardiovascular anaesthesia and intensive care • Cardiovascular surgery • Cardiovascular radiology • Clinical physiology • Transplantation of thoracic organs
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