评价新生儿止血的现代工具。我们在哪里,我们要去哪里?

IF 6.9 2区 医学 Q1 HEMATOLOGY Blood Reviews Pub Date : 2024-03-01 DOI:10.1016/j.blre.2023.101157
Rozeta Sokou , Stavroula Parastatidou , Aikaterini Konstantinidi , Andreas G. Tsantes , Nicoletta Iacovidou , Daniele Piovani , Stefanos Bonovas , Argirios E. Tsantes
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引用次数: 0

摘要

新生儿止血障碍的评估至关重要,但对临床医生来说仍然具有挑战性。尽管发育性止血的概念在全球止血专家中被广泛接受,但临床医生和实验室从业人员可能对其认识不足。随着年龄依赖性止血状态的成熟,理解正常值之间的差异对于准确诊断易受伤害的新生儿群体的潜在出血性和血栓性疾病至关重要。本文综述了发育性止血的基础知识和现有凝血检测方法的特点,重点介绍了评估新生儿止血情况的新工具。常见的错误,问题,并在新生儿止血评估陷阱讨论,随着他们对患者管理的影响。解决了当前的知识差距和研究领域。进一步的研究以提高我们对发育性止血的理解及其在日常临床实践中的反映是有必要的。
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Contemporary tools for evaluation of hemostasis in neonates. Where are we and where are we headed?

The assessment of hemostatic disorders in neonates is crucial, but remains challenging for clinicians. Although the concept of developmental hemostasis is widely accepted among hemostasis specialists globally, it is probably under-recognized by clinicians and laboratory practitioners. In parallel with age-dependent hemostatic status maturation, comprehension of the differences between normal values is crucial for the accurate diagnosis of potential hemorrhagic and thrombotic disorders of the vulnerable neonatal population. This review outlines the basics of developmental hemostasis and the features of the available coagulation testing methods, with a focus on novel tools for evaluating the neonatal hemostatic profile. Common errors, issues, and pitfalls during the assessment of neonatal hemostasis are discussed, along with their impact on patient management. Current knowledge gaps and research areas are addressed. Further studying to improve our understanding of developmental hemostasis and its reflection on everyday clinical practice is warranted.

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来源期刊
Blood Reviews
Blood Reviews 医学-血液学
CiteScore
13.80
自引率
1.40%
发文量
78
期刊介绍: Blood Reviews, a highly regarded international journal, serves as a vital information hub, offering comprehensive evaluations of clinical practices and research insights from esteemed experts. Specially commissioned, peer-reviewed articles authored by leading researchers and practitioners ensure extensive global coverage across all sub-specialties of hematology.
期刊最新文献
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