存活和死亡COVID-19患者的CBC差异:一项队列研究

Q2 Medicine Medical Journal of the Islamic Republic of Iran Pub Date : 2023-09-06 eCollection Date: 2023-01-01 DOI:10.47176/mjiri.37.97
Mahboobeh Freidoon, Narjes Soleimanifar, Naghmeh Sayadi, Hanieh Mojtahedi, Sara Assadiasl
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引用次数: 0

摘要

2019年冠状病毒病(COVID-19)大流行表明了简单、低成本和可获得的检测方法对患者分诊的重要性。全血细胞计数(CBC)可被认为是预测COVID-19预后和住院患者日常随访的良好选择。对100例入住普通病房或重症监护病房(ICU)的新冠肺炎患者进行为期10天的CBC监测。还进行了常规实验室检查。此外,在入院时计算中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)。icu组患者WBC计数明显低于非icu组(P = 0.008)。死亡组平均淋巴细胞百分比显著低于存活组(P = 0.041),而死亡组平均中性粒细胞百分比显著高于存活组(P = 0.012)。此外,幸存者的平均单核细胞百分比明显高于非幸存者(P = 0.003)。然而,两组之间的平均血小板计数、血红蛋白水平和红细胞计数没有显著差异。较低的白细胞、淋巴细胞百分比和单核细胞百分比,以及较高的中性粒细胞百分比,可能表明中重度COVID-19患者预后较差。
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CBC Differences between Survived and Deceased COVID-19 Patients: A Cohort Study.

The Coronavirus disease 2019 (COVID-19) pandemic showed the importance of simple, low-cost, and accessible tests for patient triage. Complete Blood Count (CBC) can be considered a good option for predicting the prognosis of COVID-19 and daily follow-up of hospitalized patients. CBC tests of 100 COVID-19 patients admitted to the general ward or intensive care unit (ICU) were monitored for ten days. Routine laboratory tests were also performed. In addition, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) were calculated at the time of admission. The WBC count of the ICU-admitted patients was significantly lower than in the non-ICU-admitted group (P = 0.008). The mean lymphocyte percentage of deceased patients was significantly lower than in the survived patients (P = 0.041), whereas the mean neutrophil percentage of the former group was higher than the latter ( P = 0.012). Moreover, the mean monocyte percentage of the survivors was significantly more than that of non-survivors (P = 0.003). However, there was no significant difference in mean platelet counts, hemoglobin levels, and red blood cell count between the studied groups. A lower WBC, lymphocyte percentage, and monocyte percentage, in addition to a higher neutrophil percentage, may indicate a poor prognosis in moderate to severe COVID-19 patients.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
90
审稿时长
8 weeks
期刊最新文献
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