大麻和狗和猫的病理:阿根廷兽医中植物大麻素使用的首次调查。

IF 4.1 Q1 PHARMACOLOGY & PHARMACY Journal of cannabis research Pub Date : 2023-11-29 DOI:10.1186/s42238-023-00209-5
Diana Banach, Paola Ferrero
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引用次数: 0

摘要

背景:在动物中,内源性大麻素系统调节多种生理功能。像人类一样,动物对含有植物大麻素的制剂有反应,可以治疗几种疾病。在阿根廷,第27350和27669号法律扩大了研究有益和有害影响的可能性。材料和方法:我们对阿根廷大麻兽医进行了一项基于网络的调查,对目前使用大麻素治疗狗和猫的兽医专业人员的数量进行了情境诊断。结果:在治疗的物种中,狗占77%,猫占21%。疼痛、癫痫和行为障碍是狗最常见的疾病。在猫身上治疗了七种情况和组合。从三种不同化学型中提取的全谱大麻提取物单独或与标准药物一起施用。对大麻治疗的反应是基于根据临床评估分类的改善来描述的。狗和猫的临床症状均有不同程度的改善。结论:这一分析提供了有希望的结果关于大麻在狗和猫的药用。基于这一分析,我们建议扩大专业人员的培训,获得优质制剂,并开展对照试验,以加强大麻素在兽药中的使用知识。
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Cannabis and pathologies in dogs and cats: first survey of phytocannabinoid use in veterinary medicine in Argentina.

Background: In animals, the endocannabinoid system regulates multiple physiological functions. Like humans, animals respond to preparations containing phytocannabinoids for treating several conditions. In Argentina, laws 27350 and 27669 have expanded the possibility of studying beneficial and adverse effects.

Materials and methods: We conducted a web-based survey of Argentinian Cannabis Veterinarians to make a situational diagnosis on the number of veterinary medicine professionals currently developing treatments with cannabinoids focusing on dogs and cats.  RESULTS: Among the species treated, 77% corresponded to dogs, while 21% were cats. Pain, seizures, and behavior disorders are the most prevalent conditions in dogs. Seven conditions and combinations were treated in cats. Full-spectrum cannabis extract derived from three different chemotypes was administered alone or with standard medication. Response to cannabis treatment was characterized based on improvement categorized according to clinical assessment. Both dogs and cats showed different improvement grades in clinical signs.

Conclusion: This analysis provides promising results regarding the medicinal use of cannabis in dogs and cats. Based on this analysis, we propose to expand the training of professionals, obtain quality preparations, and initiate controlled trials to reinforce knowledge of the use of cannabinoids in veterinary medicine.

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