Yu Shi Lau , Li Kuo Tan , Kok Han Chee , Chow Khuen Chan , Yih Miin Liew
{"title":"在血管内光学相干断层成像中有效的自主腔分割:揭示多项式-回归卷积神经网络的潜力","authors":"Yu Shi Lau , Li Kuo Tan , Kok Han Chee , Chow Khuen Chan , Yih Miin Liew","doi":"10.1016/j.irbm.2023.100814","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p><span>Intravascular optical coherence tomography (IVOCT) is a crucial micro-resolution </span>imaging modality<span> used to assess the internal structure of blood vessels. Lumen segmentation in IVOCT images is vital for measuring the location and the extent of vessel blockages and for guiding percutaneous coronary intervention. Obtaining such information in real-time is essential, necessitating the use of fast automated algorithms. In this paper, we proposed an innovative polynomial-regression convolutional neural network (CNN) for fast and automated IVOCT lumen segmentation.</span></p></div><div><h3>Materials and methods</h3><p>The polynomial-regression CNN architecture was uniquely crafted to enable single-pass extraction of lumen borders via IVOCT image regression, ensuring real-time processing efficiency without compromising accuracy. The architecture designed convolution for regression while omitting fully connected layers, leading to the spatial output of lumen representation as polynomial coefficients, thus enabling the formation of interconnected lumen points. The approach equipped the network to comprehend the intricate and continuous geometries and curvatures intrinsic to blood vessels in transverse and longitudinal dimensions. The network was trained on a dataset of 16,165 images and evaluated using 7,016 images.</p></div><div><h3>Results</h3><p>The predicted segmentations exhibited a distance error of less than 2 pixels (26.40 μm), Dice's coefficient of 0.982, Jaccard Index of 0.966, sensitivity of 0.980, specificity of 0.999, and a prediction time of 4 s (for a pullback containing 360 images). This technique demonstrated significantly improved performance in both accuracy and speed compared to published techniques.</p></div><div><h3>Conclusion</h3><p>The strong segmentation performance, fast speed, and robustness to image variations highlight the practical clinical utility of the proposed polynomial-regression network.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":5.6000,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficient Autonomous Lumen Segmentation in Intravascular Optical Coherence Tomography Images: Unveiling the Potential of Polynomial-Regression Convolutional Neural Network\",\"authors\":\"Yu Shi Lau , Li Kuo Tan , Kok Han Chee , Chow Khuen Chan , Yih Miin Liew\",\"doi\":\"10.1016/j.irbm.2023.100814\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p><span>Intravascular optical coherence tomography (IVOCT) is a crucial micro-resolution </span>imaging modality<span> used to assess the internal structure of blood vessels. Lumen segmentation in IVOCT images is vital for measuring the location and the extent of vessel blockages and for guiding percutaneous coronary intervention. Obtaining such information in real-time is essential, necessitating the use of fast automated algorithms. In this paper, we proposed an innovative polynomial-regression convolutional neural network (CNN) for fast and automated IVOCT lumen segmentation.</span></p></div><div><h3>Materials and methods</h3><p>The polynomial-regression CNN architecture was uniquely crafted to enable single-pass extraction of lumen borders via IVOCT image regression, ensuring real-time processing efficiency without compromising accuracy. The architecture designed convolution for regression while omitting fully connected layers, leading to the spatial output of lumen representation as polynomial coefficients, thus enabling the formation of interconnected lumen points. The approach equipped the network to comprehend the intricate and continuous geometries and curvatures intrinsic to blood vessels in transverse and longitudinal dimensions. The network was trained on a dataset of 16,165 images and evaluated using 7,016 images.</p></div><div><h3>Results</h3><p>The predicted segmentations exhibited a distance error of less than 2 pixels (26.40 μm), Dice's coefficient of 0.982, Jaccard Index of 0.966, sensitivity of 0.980, specificity of 0.999, and a prediction time of 4 s (for a pullback containing 360 images). This technique demonstrated significantly improved performance in both accuracy and speed compared to published techniques.</p></div><div><h3>Conclusion</h3><p>The strong segmentation performance, fast speed, and robustness to image variations highlight the practical clinical utility of the proposed polynomial-regression network.</p></div>\",\"PeriodicalId\":14605,\"journal\":{\"name\":\"Irbm\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.6000,\"publicationDate\":\"2023-11-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Irbm\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1959031823000635\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Irbm","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1959031823000635","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Efficient Autonomous Lumen Segmentation in Intravascular Optical Coherence Tomography Images: Unveiling the Potential of Polynomial-Regression Convolutional Neural Network
Objectives
Intravascular optical coherence tomography (IVOCT) is a crucial micro-resolution imaging modality used to assess the internal structure of blood vessels. Lumen segmentation in IVOCT images is vital for measuring the location and the extent of vessel blockages and for guiding percutaneous coronary intervention. Obtaining such information in real-time is essential, necessitating the use of fast automated algorithms. In this paper, we proposed an innovative polynomial-regression convolutional neural network (CNN) for fast and automated IVOCT lumen segmentation.
Materials and methods
The polynomial-regression CNN architecture was uniquely crafted to enable single-pass extraction of lumen borders via IVOCT image regression, ensuring real-time processing efficiency without compromising accuracy. The architecture designed convolution for regression while omitting fully connected layers, leading to the spatial output of lumen representation as polynomial coefficients, thus enabling the formation of interconnected lumen points. The approach equipped the network to comprehend the intricate and continuous geometries and curvatures intrinsic to blood vessels in transverse and longitudinal dimensions. The network was trained on a dataset of 16,165 images and evaluated using 7,016 images.
Results
The predicted segmentations exhibited a distance error of less than 2 pixels (26.40 μm), Dice's coefficient of 0.982, Jaccard Index of 0.966, sensitivity of 0.980, specificity of 0.999, and a prediction time of 4 s (for a pullback containing 360 images). This technique demonstrated significantly improved performance in both accuracy and speed compared to published techniques.
Conclusion
The strong segmentation performance, fast speed, and robustness to image variations highlight the practical clinical utility of the proposed polynomial-regression network.
期刊介绍:
IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux).
As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in:
-Physiological and Biological Signal processing (EEG, MEG, ECG…)-
Medical Image processing-
Biomechanics-
Biomaterials-
Medical Physics-
Biophysics-
Physiological and Biological Sensors-
Information technologies in healthcare-
Disability research-
Computational physiology-
…