短期空气污染暴露与中风的发病率和死亡率:一项荟萃分析。

IF 1.1 4区医学 Q4 CLINICAL NEUROLOGY Neurologist Pub Date : 2024-05-01 DOI:10.1097/NRL.0000000000000544

Wenjian Lin, Jie Pan, Jiahe Li, Xiaoyu Zhou, Xueyuan Liu

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引用次数: 0

摘要

背景:短期暴露于各种空气污染物之间的关系综述摘要:我们在数据库中进行了全面的搜索，包括PubMed, Web of Science等。采用随机效应模型估计比值比(OR)及其95% ci。短期暴露于PM10、PM2.5、NO2、SO2和O3与卒中发病率增加相关[PM2.5每增加10 μg/m3: OR = 1.005 (95% CI: 1.004-1.007)， PM10每增加10 μg/m3: OR = 1.006 (95% CI: 1.004-1.009)， SO2每增加10 μg/m3: OR = 1.034 (95% CI: 1.020-1.048)， NO2每增加10 μg/m3: OR = 1.029 (95% CI: 1.015-1.043)， O3每增加10 μg/m3: OR: 1.006 (95% CI: 1.004-1.007)]。此外，短期暴露于PM2.5、PM10、SO2和NO2与卒中死亡率增加相关[PM2.5每增加10 μg/m3: OR = 1.010 (95% CI: 1.006-1.013)， PM10每增加10 μg/m3: OR = 1.004 (95% CI: 1.003-1.006)， SO2每增加10 μg/m3: OR = 1.013 (95% CI: 1.007-1.019)， NO2每增加10 μg/m3: OR = 1.012 (95% CI: 1.008-1.015)]。结论:减少室外空气污染水平可能对降低卒中相关的发病率和死亡率产生有利的结果。

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Short-Term Exposure to Air Pollution and the Incidence and Mortality of Stroke: A Meta-Analysis.

Background: The relationship between short-term exposure to various air pollutants [particulate matter <10 μm (PM 10 ), particulate matter <2.5 μm (PM 2.5 ), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), carbon monoxide, and ozone (O 3 )] and the incidence and mortality of stroke remain unclear.

Review summary: We conducted a comprehensive search across databases, including PubMed, Web of Science, and others. A random-effects model was employed to estimate the odds ratios (OR) and their 95% CIs. Short-term exposure to PM 10 , PM 2.5 , NO 2 , SO 2 , and O 3 was associated with increased stroke incidence [per 10 μg/m 3 increase in PM 2.5 : OR = 1.005 (95% CI: 1.004-1.007), per 10 μg/m 3 increase in PM 10 : OR = 1.006 (95% CI: 1.004-1.009), per 10 μg/m 3 increase in SO 2 : OR = 1.034 (95% CI: 1.020-1.048), per 10 μg/m 3 increase in NO 2 : OR = 1.029 (95% CI: 1.015-1.043), and O 3 for per 10 μg/m 3 increase: OR: 1.006 (95% CI: 1.004-1.007)]. In addition, short-term exposure to PM 2.5 , PM 10 , SO 2, and NO 2 was correlated with increased mortality from stroke [per 10 μg/m 3 increase in PM 2.5 : OR = 1.010 (95% CI: 1.006-1.013), per 10 μg/m 3 increase in PM 10 : OR = 1.004 (95% CI: 1.003-1.006), per 10 μg/m 3 increase in SO 2 : OR = 1.013 (95% CI: 1.007-1.019) and per 10 μg/m 3 increase in NO 2 : OR = 1.012 (95% CI: 1.008-1.015)].

Conclusion: Reducing outdoor air pollutant levels may yield a favorable outcome in reducing the incidence and mortality associated with strokes.

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来源期刊

Neurologist 医学-临床神经学

CiteScore

1.90

自引率

0.00%

发文量

151

审稿时长

2 months

期刊介绍： The Neurologist publishes articles on topics of current interest to physicians treating patients with neurological diseases. The core of the journal is review articles focusing on clinically relevant issues. The journal also publishes case reports or case series which review the literature and put observations in perspective, as well as letters to the editor. Special features include the popular "10 Most Commonly Asked Questions" and the "Patient and Family Fact Sheet," a handy tear-out page that can be copied to hand out to patients and their caregivers.