青少年焦虑的生态瞬间评估:用于临床试验的心理测量学评估。

IF 1.5 4区 医学 Q2 PEDIATRICS Journal of child and adolescent psychopharmacology Pub Date : 2023-12-01 Epub Date: 2023-12-05 DOI:10.1089/cap.2023.0025
Meghan E Byrne, Rachel A Bernstein, Daniel S Pine, Katharina Kircanski
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引用次数: 0

摘要

背景:生态瞬间评估(EMA)能实时捕捉自然体验,有望提高我们对青少年心理病理学的理解和治疗水平。虽然对 EMA 方法进行心理测量学评估至关重要,尤其是在临床试验中作为一种工具使用时,但目前还缺乏对青少年 EMA 项目的可靠性和有效性的研究。研究方法:本研究评估了 204 名儿童和青少年参与者(平均年龄 = 12.54 岁,60.8% 为女性)的 EMA 反应,其中包括 131 名焦虑症患者和 73 名无精神疾病诊断的患者。我们评估了两个探查焦虑症状的 EMA 项目的人内和人际变异性、内部一致性、重测可靠性、收敛性和区分性有效性;一个积极情绪项目作为对比。结果在患有焦虑症的青少年中,焦虑项目的所有心理测量特性至少都令人满意。然而,在未确诊的青少年中,其变异性有限,测试-再测可靠性较差。讨论这些结果可能有助于未来使用 EMA 调查小儿焦虑症的临床试验。结果还表明,要可靠地追踪健康青少年的焦虑情况,可能需要独特的 EMA 项目。今后的工作应继续研究 EMA 方案的心理测量特性,然后再将其应用于临床试验中。ClinicalTrials.gov 标识符:NCT00018057。
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Ecological Momentary Assessment of Youth Anxiety: Evaluation of Psychometrics for Use in Clinical Trials.

Background: Ecological momentary assessment (EMA) captures naturalistic experience in real time and holds promise to improve our understanding and treatment of youth psychopathology. While psychometric evaluation of EMA methods is crucial, particularly for use as a tool in clinical trials, research examining the reliability and validity of EMA items in youth is lacking. Method: This study evaluates EMA responses from 204 child and adolescent participants (M age = 12.54, 60.8% female), including 131 participants with an anxiety disorder and 73 participants with no psychiatric diagnosis. We assessed the within- and between-person variability, internal consistency, test-retest reliability, and convergent and discriminant validity of two EMA items probing anxiety symptoms; one positive affect item served as a comparison. Results: All psychometric properties of the anxiety items were at least satisfactory in youth with anxiety disorders. However, there was restricted variability and poor test-retest reliability in youth with no diagnosis. Discussion: These results might facilitate future clinical trials using EMA to investigate pediatric anxiety. Results also suggest that unique EMA items might be needed to reliably track anxiety in healthy youth. Future work should continue to examine the psychometric properties of EMA protocols before implementation in clinical trials. ClinicalTrials.gov identifier: NCT00018057.

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来源期刊
CiteScore
3.60
自引率
5.30%
发文量
61
审稿时长
>12 weeks
期刊介绍: Journal of Child and Adolescent Psychopharmacology (JCAP) is the premier peer-reviewed journal covering the clinical aspects of treating this patient population with psychotropic medications including side effects and interactions, standard doses, and research on new and existing medications. The Journal includes information on related areas of medical sciences such as advances in developmental pharmacokinetics, developmental neuroscience, metabolism, nutrition, molecular genetics, and more. Journal of Child and Adolescent Psychopharmacology coverage includes: New drugs and treatment strategies including the use of psycho-stimulants, selective serotonin reuptake inhibitors, mood stabilizers, and atypical antipsychotics New developments in the diagnosis and treatment of ADHD, anxiety disorders, schizophrenia, autism spectrum disorders, bipolar disorder, eating disorders, along with other disorders Reports of common and rare Treatment Emergent Adverse Events (TEAEs) including: hyperprolactinemia, galactorrhea, weight gain/loss, metabolic syndrome, dyslipidemia, switching phenomena, sudden death, and the potential increase of suicide. Outcomes research.
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