实验动物研究中的生物安全风险控制策略

IF 3.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Safety and Health at Work Pub Date : 2024-03-01 DOI:10.1016/j.shaw.2023.11.005
Shun-tai Weng , Qu-wen Li , Ya-dong Gao , Yu-feng Qiu
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引用次数: 0

摘要

了解实验动物生物安全现状及影响职业健康的危险因素。合规调查采用中文问卷调查方式,通过网络应用软件“问卷之星”进行。收集了39份匿名问卷。被调查机构建立了24类动物生物安全实验室和配备安全设备的生物安全管理机构和体系。研究还发现,实验室设置负责人未履行监督检查职责,动物生物安全实验室设计不合理,人员培训和卫生管理不规范,废弃物管理不严格,应急管理不足。主管部门和工作单位应当对实验动物研究中的安全与职业健康风险进行处理。笔者从组织保障、人员管理、应急管理等方面提出控制策略,防范风险,保障职业健康。由于区域限制和小样本量,结果可能无法推广到世界所有地区。然而,一些关键的共同问题可能也存在于其他地区,因此我们认为这项研究仍然具有一定的相关性。
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Biosafety Risk Control Strategies in Laboratory Animal Research

To understand biosafety's current situation in laboratory animal research and risk factors affecting occupational health. Compliance surveys were conducted by questionnaire via Questionnaire Star (an application app on the Internet) in Chinese. Thirty-nine anonymous questionnaires were collected. The surveyed institution has established 24 types of ABSL (Animal Biosafety Laboratory) and biosafety management organizations and systems equipped with safety equipment. Our study also suggests that the principal of the laboratory establishment fails to perform supervision and inspection responsibilities, the inappropriate design of the animal biosafety laboratory, non-standardized personnel training and health management, non-strict waste management, and insufficient emergency management. The administrative department and work units should address certain safety and occupational health risks in laboratory animal research. The author proposes control strategies based on organizational guarantee, personnel management, emergency management, etc., to help prevent risks and ensure occupational health. Due to regional limitations and small sample size, the results may not be generalisable to all parts of the world. However, some of the key common issues may also be present in other regions, so we believe that this research still has some relevance.

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来源期刊
Safety and Health at Work
Safety and Health at Work Social Sciences-Safety Research
CiteScore
6.40
自引率
5.70%
发文量
1080
审稿时长
38 days
期刊介绍: Safety and Health at Work (SH@W) is an international, peer-reviewed, interdisciplinary journal published quarterly in English beginning in 2010. The journal is aimed at providing grounds for the exchange of ideas and data developed through research experience in the broad field of occupational health and safety. Articles may deal with scientific research to improve workers'' health and safety by eliminating occupational accidents and diseases, pursuing a better working life, and creating a safe and comfortable working environment. The journal focuses primarily on original articles across the whole scope of occupational health and safety, but also welcomes up-to-date review papers and short communications and commentaries on urgent issues and case studies on unique epidemiological survey, methods of accident investigation, and analysis. High priority will be given to articles on occupational epidemiology, medicine, hygiene, toxicology, nursing and health services, work safety, ergonomics, work organization, engineering of safety (mechanical, electrical, chemical, and construction), safety management and policy, and studies related to economic evaluation and its social policy and organizational aspects. Its abbreviated title is Saf Health Work.
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