用于估计死后时间间隔的微生物群落特征。

2区 生物学 Q1 Immunology and Microbiology Advances in applied microbiology Pub Date : 2022-03-14 DOI:10.1016/bs.aambs.2022.02.002
Hirak Ranjan Dash,Surajit Das
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引用次数: 2

摘要

人体为大量微生物的共生提供了一个复杂的生态系统。这些共生微生物通过对抗许多致命的感染,为活着的宿主提供了巨大的好处。一旦宿主死亡,人体复杂的生态系统就会发生许多变化。由于许多外源微生物在人死后攻击营养丰富的尸体,人体的个性化微生物经历了一系列的变化。人类尸体中微生物的演替模式的变化允许假设不同的模型来估计死后时间间隔(PMI)。从刑侦的角度来看,PMI估算具有广阔的应用前景。尽管目前有许多技术被用于估算PMI,但它们都有各自的优缺点。随着先进分子生物学技术的出现,对人类尸体的死亡微生物组的研究取得了进展,并为传统的PMI估算方法提供了更好的选择。本章总结了近年来人类微环境变化对死后特征菌群变化的研究进展,提出了一个估算PMI的共识模型。
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Microbial community signatures for estimation of postmortem time intervals.
The human body provides a complex ecosystem for symbiotic habitation of a huge number of microorganisms. These commensal microorganisms provide a huge benefit to the living host by acting against many deadly infections. Once the host dies, many changes in the complex ecosystem of the human body take place. The personalized microbes of a human body undergo successional change as many exogenous microbes attack the nutrient-rich cadaver after death. The succession pattern change of microbes in human cadaver allows postulating different models for estimation of Postmortem time interval (PMI). Estimation of PMI has a broad prospect from the criminal investigation point of view. Though many techniques are being used nowadays to estimate PMI, all of them have their pros and cons. With the advent of advanced molecular biological techniques, studies on the thanatomicrobiome of a human cadaver have gained pace and provide a superior alternative for conventional methods of PMI estimation. This chapter summarizes the recent advancements in the changes in signature microflora postmortem with change in human microenvironment to postulate a consensus model for estimation of PMI.
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来源期刊
Advances in applied microbiology
Advances in applied microbiology 生物-生物工程与应用微生物
CiteScore
8.20
自引率
0.00%
发文量
16
审稿时长
>12 weeks
期刊介绍: Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays.
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